The objective of the University of Michigan Center for Gastrointestinal Research (UMCGR) Administrative Core is to provide overall guidance, coordination and leadership for the Center. UMCGR Administrative Core leadership is provided by Dr. Chung Owyang, Director, and Drs. Juanita Merchant and M. Bishr Omary, Associate Directors, in conjunction with an Operations Committee, an Internal Advisory Committee, and an External Advisory Committee. The Operations Committee is comprised of the Director, at least one of the Associate Directors, at least one Core Director and other Center Investigators selected to serve three year renewable terms. The Operations Committee meets monthly and assists the Director in establishing the policies and plans of the Center and in reviewing the operations of the Center. On a yearly basis it reviews and approves all budgetary allocations as well as final allocations for Pilot/Feasibility Awards. The Internal Advisory Committee meets in formal sessions every year to review the operations and accomplishments of the Center and to provide counsel in areas of policy, administration, management and facilitates communication with institutional leaders to ensure that the Center remains responsive to overall institutional needs. The External Advisory Committee consists of five internationally prominent investigators who are leaders in digestive disease research and meets annually in person and by conference call as needed to provide regular feedback to the Executive Committee. An Administrator and Administrative Assistant provide the necessary support for real-time financial management and operations of the Center. The Executive Committee consists of the Director, both of the Associate Directors, the Administrator and Administrative Assistant and meets quarterly to plan and manage the UMCGR operations. The administrative leadership assures responsiveness of the UMCGR Cores to the needs of the Research Base and provides oversight for Core functions. UMCGR's many goals include the promotion of cutting edge digestive disease related research by: i) fostering collaborative, multidisciplinary research by expanding the technical and collaborative capabilities of established GI scientists and by attracting investigators from other disciplines; ii) implementing a robust Scientific Enrichment Program that includes research-in-progress seminars, academic workshops, an annual research retreat, and a semi-monthly visiting faculty seminar program; iii) nurturing new GI investigators via a peer reviewed, widely publicized Pilot and Feasibility Program; and, iv) promoting synergistic interaction between the Michigan Institute for Clinical and Health Research (MICHR), which houses the NIH-sponsored Michigan Clinical and Translational Science Award (CTSA) and the Michigan Clinical Research Center (MCRU), the NIDDK funded Michigan Nutrition and Obesity Research Center (MNORC) and Michigan Diabetes Research Center (MDRC), and among other DDRCCs including the Midwest DDRCC Alliance.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK034933-31A1
Application #
9312969
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2017-04-01
Budget End
2018-03-31
Support Year
31
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Cruz-Acuña, Ricardo; Quirós, Miguel; Huang, Sha et al. (2018) PEG-4MAL hydrogels for human organoid generation, culture, and in vivo delivery. Nat Protoc 13:2102-2119
Ye, Wei; Takabayashi, Hidehiko; Yang, Yitian et al. (2018) Regulation of Gastric Lgr5+ve Cell Homeostasis by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli. Cell Mol Gastroenterol Hepatol 5:523-538
Brady, Graham F; Kwan, Raymond; Bragazzi Cunha, Juliana et al. (2018) Lamins and Lamin-Associated Proteins in Gastrointestinal Health and Disease. Gastroenterology 154:1602-1619.e1
Hu, Yongjun; Song, Feifeng; Jiang, Huidi et al. (2018) SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages. J Immunol 201:652-662
McClintock, Shannon D; Colacino, Justin A; Attili, Durga et al. (2018) Calcium-Induced Differentiation of Human Colon Adenomas in Colonoid Culture: Calcium Alone versus Calcium with Additional Trace Elements. Cancer Prev Res (Phila) 11:413-428
Kim, Geun Hyang; Shi, Guojun; Somlo, Diane Rm et al. (2018) Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity. J Clin Invest 128:1125-1140
Wang, Xuexiang; Dande, Ranadheer R; Yu, Hao et al. (2018) TRPC5 Does Not Cause or Aggravate Glomerular Disease. J Am Soc Nephrol 29:409-415
Bhattacharya, Asmita; Sun, Shengyi; Wang, Heting et al. (2018) Hepatic Sel1L-Hrd1 ER-associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH. EMBO J 37:
Perry, Jeffrey W; Tai, Andrew W (2018) Random Insertional Mutagenesis of a Serotype 2 Dengue Virus Clone. Bio Protoc 8:
El-Zaatari, Mohamad; Bass, Adam J; Bowlby, Reanne et al. (2018) Indoleamine 2,3-Dioxygenase 1, Increased in Human Gastric Pre-Neoplasia, Promotes Inflammation and Metaplasia in Mice and Is Associated With Type II Hypersensitivity/Autoimmunity. Gastroenterology 154:140-153.e17

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