The Administrative Core provides operational and financial oversight for the DDRCC. The Core is responsible for administering the DDRCC grant assuring that the Center is in compliance with federal regulations, that reports are submitted in a timely fashion, and that the budget is balanced. The Administrative Core manages the expenditures and charge-backs for the science cores. The Center Administrator helps organize the pilot feasibility program, meetings of the directors, executive committee and scientific review committee. The Administrator manages the enrichment program and the budget. The Center is directed by two co-directors: Robert Sandler and R. Balfour Sartor. They are assisted by two Associate Directors, Susan Henning (career development) and Nicholas Shaheen (clinical translational research). Administratively, the CGIBD is equivalent to a department on our campus which means the directors report directly to the dean, the Center has its own designated space for cores, and a portion of indirect costs from grants originating in the Center are returned ($485,831 last year). Returned indirects support administrative staff, human resources, IT and capital equipment. An Executive Committee composed of directors, two scientists from each campus and one at large member establish goals, set standards of use of cores, review P/F studies, elect members, plan the enrichment program and interact with the external Scientific Review Committee (SRC). Members of the SRC are: Kim Barrett, PhD, Gail Hecht, MD, Nicholas Davidson, MD and Gary Wu, MD. The SRC rigorously evaluates the scientific goals, progress, core use, and P/F program. They select P/F projects after application review and oral presentations by applicants. An active enrichment program includes: a weekly research seminar that includes visiting experts, annual research competition, poster competition and practice sessions. The center also sponsors day-long symposia.

Public Health Relevance

The Administrative Core provides operational and financial oversight for the DDRCC. The Core is responsible for assuring that the Center is in compliance with federal regulations, that reports are submitted, and that the budget is balanced. The Administrative Core manages an active Enrichment Program of seminars and symposia. The Core helps Center investigators conduct research to prevent or manage disease.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034987-32
Application #
9198002
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2016-12-01
Budget End
2017-11-30
Support Year
32
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Zhang, Cun-Jin; Wang, Chenhui; Jiang, Meiling et al. (2018) Act1 is a negative regulator in T and B cells via direct inhibition of STAT3. Nat Commun 9:2745
Evon, Donna M; Golin, Carol E; Ruffin, Rachel et al. (2018) Novel patient-reported outcomes (PROs) used in a pilot and feasibility study of a Cognitive Behavioral Coping Skills (CBCS) group intervention for patients with chronic hepatitis C. Pilot Feasibility Stud 4:92
Busch, Evan L; Don, Prabhani Kuruppumullage; Chu, Haitao et al. (2018) Diagnostic accuracy and prediction increment of markers of epithelial-mesenchymal transition to assess cancer cell detachment from primary tumors. BMC Cancer 18:82
Herfarth, Hans; Barnes, Edward L; Valentine, John F et al. (2018) Methotrexate Is Not Superior to Placebo in Maintaining Steroid-Free Response or Remission in Ulcerative Colitis. Gastroenterology 155:1098-1108.e9
Koutlas, N T; Eluri, S; Rusin, S et al. (2018) Impact of smoking, alcohol consumption, and NSAID use on risk for and phenotypes of eosinophilic esophagitis. Dis Esophagus 31:1-7
Reese, Aspen T; Cho, Eugenia H; Klitzman, Bruce et al. (2018) Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut. Elife 7:
Walker, Miriam Y; Pratap, Siddharth; Southerland, Janet H et al. (2018) Role of oral and gut microbiome in nitric oxide-mediated colon motility. Nitric Oxide 73:81-88
Smid, Marcela C; Ricks, Nitasha M; Panzer, Alexis et al. (2018) Maternal Gut Microbiome Biodiversity in Pregnancy. Am J Perinatol 35:24-30
Gracz, Adam D; Samsa, Leigh Ann; Fordham, Matthew J et al. (2018) Sox4 Promotes Atoh1-Independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates. Gastroenterology 155:1508-1523.e10
Keith, Benjamin P; Barrow, Jasmine B; Toyonaga, Takahiko et al. (2018) Colonic epithelial miR-31 associates with the development of Crohn's phenotypes. JCI Insight 3:

Showing the most recent 10 out of 944 publications