This Core facility is the administrative structure of the Liver Research Center. The activities include all scientific and administrative supervisory functions of the Center and its administrative leadership, including the organization and supervision of Core facilities, the planning and scheduling of the enrichment program and the review of individual pilot feasibility projects. All fiscal records and accounts for the Core's Pilot Projects are fully computerized and analysis sheets are now distributed electronically to principal investigators on a monthly basis. The Core provides administrative support for the Executive Committee (Drs. Boyer, Cheng, Flavell, Garcia-Tsao, Groszmann, Nathanson and Strazzabosco) as well as organizing and facilitating Liver Center seminars including visiting speakers and annual meetings of the External Advisory Board.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK034989-30
Application #
8515996
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
30
Fiscal Year
2013
Total Cost
$813,264
Indirect Cost
$456,711
Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520
Birkenfeld, Andreas L; Shulman, Gerald I (2014) Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. Hepatology 59:713-23
Cai, Shi-Ying; Mennone, Albert; Soroka, Carol J et al. (2014) Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice. Am J Physiol Gastrointest Liver Physiol 306:G670-6
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Cai, Shi-Ying; Mennone, Albert; Soroka, Carol J et al. (2014) All-trans-retinoic acid improves cholestasis in ?-naphthylisothiocyanate-treated rats and Mdr2-/- mice. J Pharmacol Exp Ther 349:94-8
Hedl, Matija; Abraham, Clara (2014) A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1. Proc Natl Acad Sci U S A 111:13451-6
Strazzabosco, Mario; Fabris, Luca (2014) Neural cell adhesion molecule and polysialic acid in ductular reaction: the puzzle is far from completed, but the picture is becoming more clear. Hepatology 60:1469-72
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Chen, Jianxin; Wong, Serena; Nathanson, Michael H et al. (2014) Evaluation of Barrett esophagus by multiphoton microscopy. Arch Pathol Lab Med 138:204-12
Hedl, Matija; Lahiri, Amit; Ning, Kaida et al. (2014) Pattern recognition receptor signaling in human dendritic cells is enhanced by ICOS ligand and modulated by the Crohn's disease ICOSLG risk allele. Immunity 40:734-46

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