The Morphology Core Facility provides instrumentation and technical expertise for the preparation, acquisition and analysis of images of cells and tissues at both the light and electron microscopic level. Given the cost of such instrumentation and the high level of technical expertise required to perform these investigational techniques, this Core was established to ensure the availability of these techniques for Center members.'In recognition of the broad usefulness of this Core facility, the School of Medicine has partnered with the Liver Center by making ongoing, major investments to ensure that the facility remains stateof- the-art, as outlined below.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Yale University
New Haven
United States
Zip Code
Birkenfeld, Andreas L; Shulman, Gerald I (2014) Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. Hepatology 59:713-23
Cai, Shi-Ying; Mennone, Albert; Soroka, Carol J et al. (2014) Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice. Am J Physiol Gastrointest Liver Physiol 306:G670-6
Kuo, Ivana Y; DesRochers, Teresa M; Kimmerling, Erica P et al. (2014) Cyst formation following disruption of intracellular calcium signaling. Proc Natl Acad Sci U S A 111:14283-8
Hedl, Matija; Zheng, Shasha; Abraham, Clara (2014) The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways. J Immunol 192:5924-32
Cai, Shi-Ying; Mennone, Albert; Soroka, Carol J et al. (2014) All-trans-retinoic acid improves cholestasis in ?-naphthylisothiocyanate-treated rats and Mdr2-/- mice. J Pharmacol Exp Ther 349:94-8
Hedl, Matija; Abraham, Clara (2014) A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1. Proc Natl Acad Sci U S A 111:13451-6
Strazzabosco, Mario; Fabris, Luca (2014) Neural cell adhesion molecule and polysialic acid in ductular reaction: the puzzle is far from completed, but the picture is becoming more clear. Hepatology 60:1469-72
Amaya, Maria J; Oliveira, Andre G; Guimaraes, Erika S et al. (2014) The insulin receptor translocates to the nucleus to regulate cell proliferation in liver. Hepatology 59:274-83
Chen, Jianxin; Wong, Serena; Nathanson, Michael H et al. (2014) Evaluation of Barrett esophagus by multiphoton microscopy. Arch Pathol Lab Med 138:204-12
Hedl, Matija; Lahiri, Amit; Ning, Kaida et al. (2014) Pattern recognition receptor signaling in human dendritic cells is enhanced by ICOS ligand and modulated by the Crohn's disease ICOSLG risk allele. Immunity 40:734-46

Showing the most recent 10 out of 440 publications