The main objective of the Boston University Pilot and Feasibility (P&F) Program is to catalyze transformative advances in both translational and basic diabetes research, expanding and broadening the innovative parent Joslin P&F program. The new program would be integrated into the parent Joslin P&F program and will adopt its administrative and scientific policies and infrastructure. The program will have two main components: a regional Computational Systems Biology program and a Boston University Medical Center based new investigator program. The majority of the researchers enrolled in the new Computational Systems Biology program are either new or well-established systems biology researchers at BU, MIT or Harvard with limited prior research in diabetes or metabolic diseases. Thus, the scientific benefits from this program are expected to be high since these researchers bring a substantial prior track record in systems biology or network research successfully applied in other biomedical areas, but they have not previously worked in the biology, genetics or translational aspects of diabetes. The BU Medical Center program will emphasize funding new investigators who work in areas complementary to the focus areas of the Joslin primary P&F program and will include cardiovascular complications related to diabetes and obesity.
The new Pilot and Feasibility Grant Program at Boston University provides seed grants to attract new researchers to the diabetes field. It specifically funds 1. New investigators in the diabetes field who have not previously received substantial NIH funding;2. Experienced investigators in the diabetes field who wish to strike out in a novel direction;and 3. Investigators from other fields embarking on a diabetes-related project for the first time.
|Pavkov, Meda E; Nelson, Robert G; Knowler, William C et al. (2015) Elevation of circulating TNF receptors 1 and 2 increases the risk of end-stage renal disease in American Indians with type 2 diabetes. Kidney Int 87:812-9|
|Avadhani, Radhika; Fowler, Kristen; Barbato, Corinne et al. (2015) Glycemia and cognitive function in metabolic syndrome and coronary heart disease. Am J Med 128:46-55|
|Baskaran, Charumathi; Volkening, Lisa K; Diaz, Monica et al. (2015) A decade of temporal trends in overweight/obesity in youth with type 1 diabetes after the Diabetes Control and Complications Trial. Pediatr Diabetes 16:263-70|
|Rasbach, Lisa; Jenkins, Carolyn; Laffel, Lori (2015) An integrative review of self-efficacy measurement instruments in youth with type 1 diabetes. Diabetes Educ 41:43-58|
|Castiglioni, Alessandra; Hettmer, Simone; Lynes, Matthew D et al. (2014) Isolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle. Stem Cell Reports 2:92-106|
|Markowitz, Jessica T; Volkening, Lisa K; Laffel, Lori M B (2014) Care utilization in a pediatric diabetes clinic: cancellations, parental attendance, and mental health appointments. J Pediatr 164:1384-9|
|Isganaitis, Elvira; Woo, Melissa; Ma, Huijuan et al. (2014) Developmental programming by maternal insulin resistance: hyperinsulinemia, glucose intolerance, and dysregulated lipid metabolism in male offspring of insulin-resistant mice. Diabetes 63:688-700|
|Teo, Adrian Kee Keong; Valdez, Ivan Achel; Dirice, Ercument et al. (2014) Comparable generation of activin-induced definitive endoderm via additive Wnt or BMP signaling in absence of serum. Stem Cell Reports 3:5-14|
|Lee, Hyung-Yul; Wei, Dan; Loeken, Mary R (2014) Lack of metformin effect on mouse embryo AMPK activity: implications for metformin treatment during pregnancy. Diabetes Metab Res Rev 30:23-30|
|Sanders, Kaitlyn; Jung, Jin Hyuk; Loeken, Mary R (2014) Use of a murine embryonic stem cell line that is sensitive to high glucose environment to model neural tube development in diabetic pregnancy. Birth Defects Res A Clin Mol Teratol 100:584-91|
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