THE PROPOSED SPECIFIC AIMS OF THE CELL BIOLOGY CORE ARE TO PROVIDE: 1. Space, supplies, and access to sophisticated equipment used in morphology, cell culture, and immunology 2. Specific training and supervision for utilizing specialized techniques and equipment 3. Expert consultative services in research design 4. Efficient coordinated acquisition of data and data interpretation 5. Enrichment courses in basic concepts in molecular cell biology, nutrition interaction with Gl immunology. Proposed core services provided by the NORC-H Cell Biology Core include: 1. Individual assistance, training and supervision for using specialized techniques and equipment. 2. Consultative services for morphological, immunological and tissue culture experiments. 3. Research instrumentation, technical support, and expertise in morphology, immunology and cell culture. 4. Data acquisition, analysis and interpretation. 5. Formal courses on basic concepts in molecular cell biology, and nutrition interaction with Gl immunology (at an affordable cost).

Agency
National Institute of Health (NIH)
Type
Center Core Grants (P30)
Project #
5P30DK040561-18
Application #
8715764
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
Budget End
Support Year
18
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Oliveira, Adriana L; Azevedo, Debora C; Bredella, Miriam A et al. (2015) Visceral and subcutaneous adipose tissue FDG uptake by PET/CT in metabolically healthy obese subjects. Obesity (Silver Spring) 23:286-9
Houghteling, Pearl D; Walker, W Allan (2015) Why is initial bacterial colonization of the intestine important to infants' and children's health? J Pediatr Gastroenterol Nutr 60:294-307
Shanmugam, Nanda Kumar N; Trebicka, Estela; Fu, Ling-Lin et al. (2014) Intestinal inflammation modulates expression of the iron-regulating hormone hepcidin depending on erythropoietic activity and the commensal microbiota. J Immunol 193:1398-407
Makimura, Hideo; Murphy, Caitlin A; Feldpausch, Meghan N et al. (2014) The effects of tesamorelin on phosphocreatine recovery in obese subjects with reduced GH. J Clin Endocrinol Metab 99:338-43
Duro, Debora; Mitchell, Paul D; Mehta, Nilesh M et al. (2014) Variability of resting energy expenditure in infants and young children with intestinal failure-associated liver disease. J Pediatr Gastroenterol Nutr 58:637-41
Kraus, Daniel; Yang, Qin; Kong, Dong et al. (2014) Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature 508:258-62
Gathungu, Rose M; Bird, Susan S; Sheldon, Diane P et al. (2014) Identification of metabolites from liquid chromatography-coulometric array detection profiling: gas chromatography-mass spectrometry and refractionation provide essential information orthogonal to LC-MS/microNMR. Anal Biochem 454:23-32
Weng, Meiqian; Ganguli, Kriston; Zhu, Weishu et al. (2014) Conditioned medium from Bifidobacteria infantis protects against Cronobacter sakazakii-induced intestinal inflammation in newborn mice. Am J Physiol Gastrointest Liver Physiol 306:G779-87
Sanderson, Ian R (2014) Growth problems in children with IBD. Nat Rev Gastroenterol Hepatol 11:601-10
Su, Libo; Su, Chien-wen; Qi, Yujuan et al. (2014) Coinfection with an intestinal helminth impairs host innate immunity against Salmonella enterica serovar Typhimurium and exacerbates intestinal inflammation in mice. Infect Immun 82:3855-66

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