Abstract

The overall goal of the CURE: DDRCC is to promote multidisciplinary research in the molecular and cell biology, physiology and pathophysiology of the digestive system, foster collaboration and facilitate training, education and recruitment of new investigators. The Pilot and Feasibility Studies (PFS) Program, which has been enhanced by partnering with the UCLA Center for Translational Science Institute (CTSI) and by direct institutional resources (see below), is a key component to achieve the goals of the Center. The leverage of PFS funds has provided an important mechanism for enhancing our PFS program via substantial institutional support. We anticipate that a similar enhancement of the PFS program will operate in the next funding period.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK041301-29
Application #
9392156
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2017-12-01
Budget End
2018-11-30
Support Year
29
Fiscal Year
2018
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Osadchiy, Vadim; Labus, Jennifer S; Gupta, Arpana et al. (2018) Correlation of tryptophan metabolites with connectivity of extended central reward network in healthy subjects. PLoS One 13:e0201772
May, Folasade P; Yu, Christine; Kaunitz, Jonathan (2018) High quality of cancer care in the Department of Veterans Affairs (VA). Am J Cancer Res 8:761-762
Freise, Amanda C; Zettlitz, Kirstin A; Salazar, Felix B et al. (2018) Immuno-PET in Inflammatory Bowel Disease: Imaging CD4-Positive T Cells in a Murine Model of Colitis. J Nucl Med 59:980-985
Nih, Lina R; Gojgini, Shiva; Carmichael, S Thomas et al. (2018) Dual-function injectable angiogenic biomaterial for the repair of brain tissue following stroke. Nat Mater 17:642-651
Severino, Amie; Chen, Wenling; Hakimian, Joshua K et al. (2018) Mu-opioid receptors in nociceptive afferents produce a sustained suppression of hyperalgesia in chronic pain. Pain 159:1607-1620
Mirshafiee, Vahid; Sun, Bingbing; Chang, Chong Hyun et al. (2018) Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages versus Apoptosis in Hepatocytes. ACS Nano 12:3836-3852
Ali, Ayub; Ng, Hwee L; Blankson, Joel N et al. (2018) Highly Attenuated Infection With a Vpr-Deleted Molecular Clone of Human Immunodeficiency Virus-1. J Infect Dis 218:1447-1452
Pothoulakis, Charalabos; Torre-Rojas, Monica; Duran-Padilla, Marco A et al. (2018) CRHR2/Ucn2 signaling is a novel regulator of miR-7/YY1/Fas circuitry contributing to reversal of colorectal cancer cell resistance to Fas-mediated apoptosis. Int J Cancer 142:334-346
Martin, Clair R; Osadchiy, Vadim; Kalani, Amir et al. (2018) The Brain-Gut-Microbiome Axis. Cell Mol Gastroenterol Hepatol 6:133-148
Olson, Christine A; Vuong, Helen E; Yano, Jessica M et al. (2018) The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet. Cell 173:1728-1741.e13

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