The Boston Nutrition Obesity Research Center (BNORC) was founded in 1992 and has been administratively based at Boston Medical Center (BMC) for the past 15 years. The BNORC consortium is a collaboration of Boston, Tufts, and Harvard Universities and serves nutrition and obesity scientists in the Boston area. The overall objective of BNORC is to 1) facilitate and support the conduct of cutting edge basic and translational research in the fields of nutrition and obesity science, and 2) provide resources and educational opportunities that enrich the training of new investigators and promote multi- and interdisciplinary research collaborations. Four Cores serve these goals: A) Administrative (S.K. Fried, Director), B) Adipose Biology and Nutnent Metabolism (S.K. Fried and A.S. Greenberg), C) Clinical and Community Research (A. Must and E. Goodman), D) Epidemiology and Genetics (F. Hu and J. Chavarro), and E) Transgenic (B. Lowell). The BNORC research base includes 164 members with $42 million of nutrition and obesity related federal funding (24.0% NIDDK; 70% federal). These scientists address basic, clinical and population aspects of four interrelated themes: 1) Nutrient Metabolism in Health and Disease; 2) Brain Control of Feeding Behavior and Metabolism; 3) Environmental and Genetic Influence of Obesity and Related Chronic Diseases; and 4) Multi-level, Lifecourse Approaches to Nutrition and Obesity -related Diseases. Substantial resources are dedicated to our Pilot and Feasibility Program which has supported the early careers of many prominent scientists in the field.

Public Health Relevance

Approximately 34% of adult Americans and 18% of children are obese, substantially increasing the risk of a number of chronic diseases such as diabetes, heart disease, osteoarthritis and some cancers. Diet quality also affects risk of chronic disease. By bridging disciplines and promoting collaborations, the Boston Nutrition Obesity Research Center fosters the development of strategies to improve the health of many of our citizens.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
4P30DK046200-24
Application #
9263378
Study Section
Special Emphasis Panel (ZDK1)
Program Officer
Evans, Mary
Project Start
Project End
Budget Start
2016-04-01
Budget End
2017-03-31
Support Year
24
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
Marron, Elena M; Viejo-Sobera, Raquel; Cuatrecasas, Guillem et al. (2018) Prefronto-cerebellar neuromodulation affects appetite in obesity. Int J Obes (Lond) :
Dong, Kimberly R; Must, Aviva; Tang, Alice M et al. (2018) Food Insecurity, Morbidities, and Substance Use in Adults on Probation in Rhode Island. J Urban Health 95:564-575
Chiu, Yu-Han; Bertrand, Kimberly A; Zhang, Shumin et al. (2018) A prospective analysis of circulating saturated and monounsaturated fatty acids and risk of non-Hodgkin lymphoma. Int J Cancer 143:1914-1922
Yamamoto, Ayae; Harris, Holly R; Vitonis, Allison F et al. (2018) A prospective cohort study of meat and fish consumption and endometriosis risk. Am J Obstet Gynecol 219:178.e1-178.e10
Todd, William D; Fenselau, Henning; Wang, Joshua L et al. (2018) A hypothalamic circuit for the circadian control of aggression. Nat Neurosci 21:717-724
Perng, Wei; Rifas-Shiman, Sheryl L; Hivert, Marie-France et al. (2018) Branched Chain Amino Acids, Androgen Hormones, and Metabolic Risk Across Early Adolescence: A Prospective Study in Project Viva. Obesity (Silver Spring) 26:916-926
Kim, Hanseul; Keum, NaNa; Giovannucci, Edward L et al. (2018) Garlic intake and gastric cancer risk: Results from two large prospective US cohort studies. Int J Cancer 143:1047-1053
Heianza, Yoriko; Sun, Dianjianyi; Smith, Steven R et al. (2018) Changes in Gut Microbiota-Related Metabolites and Long-term Successful Weight Loss in Response to Weight-Loss Diets: The POUNDS Lost Trial. Diabetes Care 41:413-419
Chistol, Liem T; Bandini, Linda G; Must, Aviva et al. (2018) Sensory Sensitivity and Food Selectivity in Children with Autism Spectrum Disorder. J Autism Dev Disord 48:583-591
Thomas, Dylan D; Istfan, Nawfal W; Bistrian, Bruce R et al. (2018) Protein sparing therapies in acute illness and obesity: a review of George Blackburn's contributions to nutrition science. Metabolism 79:83-96

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