Abstract

The overall theme of the Metabolic Core lab is to support investigation of insulin resistance, obesity, and inflammation from a cellular/molecular perspective. The Metabolic Core provides consultation and analysis of insulin signaling, hormone assays, qPCR, insulin clamping (mice, rats), and cell based assays of cytokines and adipokines tailored to the investigators needs. Over the last grant period the Metabolic Core has developed expertise in multiplex based cytokine analysis. Most recently the Metabolic Core received NIH funding to purchase a Seahorse XF24-3 extracellular flux analyzer to allow us to begin to interrogate mitochondrial function.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK048520-20
Application #
8730600
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2014-08-01
Budget End
2015-07-31
Support Year
20
Fiscal Year
2014
Total Cost
$218,149
Indirect Cost
$71,819

  Institution

Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

McCulloch, Alan F; Jauregui, Ruy; Maclean, Paul H et al. (2018) An entropy-reducing data representation approach for bioinformatic data. Database (Oxford) 2018:
Monks, Jenifer; Orlicky, David J; Stefanski, Adrianne L et al. (2018) Maternal obesity during lactation may protect offspring from high fat diet-induced metabolic dysfunction. Nutr Diabetes 8:18
Brown, Candace S; Masters, Kevin S; Huebschmann, Amy G (2018) Identifying Motives of Midlife Black Triathlete Women Using Survey Transformation to Guide Qualitative Inquiry. J Cross Cult Gerontol 33:1-20
Rossman, Matthew J; Santos-Parker, Jessica R; Steward, Chelsea A C et al. (2018) Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults. Hypertension 71:1056-1063
MacLean, Paul S; Rothman, Alexander J; Nicastro, Holly L et al. (2018) The Accumulating Data to Optimally Predict Obesity Treatment (ADOPT) Core Measures Project: Rationale and Approach. Obesity (Silver Spring) 26 Suppl 2:S6-S15
Chan, Christine L; Vigers, Timothy; Pyle, Laura et al. (2018) Continuous glucose monitoring abnormalities in cystic fibrosis youth correlate with pulmonary function decline. J Cyst Fibros 17:783-790
Speaker, K J; Sayer, R D; Peters, J C et al. (2018) Effects of consuming a high-protein diet with or without soy protein during weight loss and maintenance: a non-inferiority, randomized clinical efficacy trial. Obes Sci Pract 4:357-366
Hijmans, Jamie G; Diehl, Kyle J; Bammert, Tyler D et al. (2018) Association between hypertension and circulating vascular-related microRNAs. J Hum Hypertens 32:440-447
Soti, Subada; Corey, Kathleen E; Lake, Jordan E et al. (2018) NAFLD and HIV: Do Sex, Race, and Ethnicity Explain HIV-Related Risk? Curr HIV/AIDS Rep 15:212-222
Carlson, Nicole S; Corwin, Elizabeth J; Hernandez, Teri L et al. (2018) Association between provider type and cesarean birth in healthy nulliparous laboring women: A retrospective cohort study. Birth 45:159-168

Showing the most recent 10 out of 756 publications