Abstract

The objective of the Obesity and Energy Metabolism Core is to provide center investigators with the latest toolsfor developing and evaluating gain-of-function and loss-of-function models and the techniques to assess theconsequences at the level of gene and/or protein expression. The Core will facilitate rapid and cost-effectiveacquisition of research results of participating investigators by providing access, training, and expertise in keymolecular technology platforms used in obesity research. For this purpose, the core services are divided intofour main components: the Virus Production facility, Microarray Analysis facility, Real Time PCR facility andMass Spectrometry and Proteomics facility.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK050456-11
Application #
7120310
Study Section
Special Emphasis Panel (ZDK1-GRB-W (J1))
Project Start
2006-04-01
Project End
2011-03-31
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
11
Fiscal Year
2006
Total Cost
$166,349
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Roelfsema, Ferdinand; Yang, Rebecca J; Takahashi, Paul Y et al. (2018) Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men. J Clin Endocrinol Metab 103:4419-4427
Xu, Ming; Pirtskhalava, Tamar; Farr, Joshua N et al. (2018) Senolytics improve physical function and increase lifespan in old age. Nat Med 24:1246-1256
Gross, Amy C; Kaizer, Alexander M; Ryder, Justin R et al. (2018) Relationships of Anxiety and Depression with Cardiovascular Health in Youth with Normal Weight to Severe Obesity. J Pediatr 199:85-91
Chung, Jin Ook; Koutsari, Christina; Blachnio-Zablieska, Agnieszka Urszula et al. (2018) Effects of meal ingestion on intramyocellular ceramide concentrations and fractional de novo synthesis in humans. Am J Physiol Endocrinol Metab 314:E105-E114
Fyfe-Johnson, Amber L; Ryder, Justin R; Alonso, Alvaro et al. (2018) Ideal Cardiovascular Health and Adiposity: Implications in Youth. J Am Heart Assoc 7:
Reid, Brie M; Harbin, Michelle M; Arend, Jessica L et al. (2018) Early Life Adversity with Height Stunting Is Associated with Cardiometabolic Risk in Adolescents Independent of Body Mass Index. J Pediatr 202:143-149
Smith, Kathryn E; Mason, Tyler B; Crosby, Ross D et al. (2018) State and trait positive and negative affectivity in relation to restraint intention and binge eating among adults with obesity. Appetite 120:327-334
McGee-Lawrence, Meghan E; Pierce, Jessica L; Yu, Kanglun et al. (2018) Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity. J Cell Physiol 233:2671-2680
Pfister, Katie M; Zhang, Lei; Miller, Neely C et al. (2018) Early body composition changes are associated with neurodevelopmental and metabolic outcomes at 4 years of age in very preterm infants. Pediatr Res 84:713-718
Roelfsema, Ferdinand; Yang, Rebecca J; Veldhuis, Johannes D (2018) Differential Effects of Estradiol and Progesterone on Cardiovascular Risk Factors in Postmenopausal Women. J Endocr Soc 2:794-805

Showing the most recent 10 out of 717 publications