The public health significance of disordered eating behavior is great. These are relatively common disorders, affecting primarily women;overall at least 2.5% ofthe population is affected.(1,2) Rates of less severe but still disordered eating among teens and college students are higher still. Population-based studies show that 7% of adolescent females and 3% of adolescent boys report using unhealthy weight control behaviors, such as purging or skipping meals, to manage their weight."""""""" The economic and social burdeps of eating disorders are substantial.(8,9) Medical complications are extremely common and the rate of mortality is very high. In fact, welldesigned studies have found a mortality rate in anorexia nervosa of over one half percent per year(10,11) and recent evidence documents elevated mortality in other eating disorders as well.(12) Moreover, disordered eating may be important to our understanding of the causes, prevention, and treatment of obesity. For example, patterns of binge eating and night eating in obese individuals have been recognized for over 50 years(13) The phenomenon of binge eating has been a topic of increased interest and controversy over the last 15-20 years. In summary, disordered eating has a high prevalence rate, significant medical and psychosocial co-morbidities, and important implications for treating and preventing obesity. For these reasons, a Disordered Eating Behavior Core is a valuable component ofthe center.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK050456-16
Application #
8132704
Study Section
Special Emphasis Panel (ZDK1-GRB-2 (J2))
Project Start
2011-04-01
Project End
2016-03-31
Budget Start
2011-04-01
Budget End
2012-03-31
Support Year
16
Fiscal Year
2011
Total Cost
$124,221
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Espinosa De Ycaza, A E; Donegan, D; Jensen, M D (2018) Long-term metabolic risk for the metabolically healthy overweight/obese phenotype. Int J Obes (Lond) 42:302-309
Jahansouz, C; Xu, H; Hertzel, A V et al. (2018) Partitioning of adipose lipid metabolism by altered expression and function of PPAR isoforms after bariatric surgery. Int J Obes (Lond) 42:139-146
Roelfsema, Ferdinand; Yang, Rebecca J; Takahashi, Paul Y et al. (2018) Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men. J Clin Endocrinol Metab 103:4419-4427
Xu, Ming; Pirtskhalava, Tamar; Farr, Joshua N et al. (2018) Senolytics improve physical function and increase lifespan in old age. Nat Med 24:1246-1256
Gross, Amy C; Kaizer, Alexander M; Ryder, Justin R et al. (2018) Relationships of Anxiety and Depression with Cardiovascular Health in Youth with Normal Weight to Severe Obesity. J Pediatr 199:85-91
Chung, Jin Ook; Koutsari, Christina; Blachnio-Zablieska, Agnieszka Urszula et al. (2018) Effects of meal ingestion on intramyocellular ceramide concentrations and fractional de novo synthesis in humans. Am J Physiol Endocrinol Metab 314:E105-E114
Fyfe-Johnson, Amber L; Ryder, Justin R; Alonso, Alvaro et al. (2018) Ideal Cardiovascular Health and Adiposity: Implications in Youth. J Am Heart Assoc 7:
Reid, Brie M; Harbin, Michelle M; Arend, Jessica L et al. (2018) Early Life Adversity with Height Stunting Is Associated with Cardiometabolic Risk in Adolescents Independent of Body Mass Index. J Pediatr 202:143-149
Smith, Kathryn E; Mason, Tyler B; Crosby, Ross D et al. (2018) State and trait positive and negative affectivity in relation to restraint intention and binge eating among adults with obesity. Appetite 120:327-334
McGee-Lawrence, Meghan E; Pierce, Jessica L; Yu, Kanglun et al. (2018) Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity. J Cell Physiol 233:2671-2680

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