The public health significance of disordered eating behavior is great. These are relatively common disorders, affecting primarily women;overall at least 2.5% ofthe population is affected.(1,2) Rates of less severe but still disordered eating among teens and college students are higher still. Population-based studies show that 7% of adolescent females and 3% of adolescent boys report using unhealthy weight control behaviors, such as purging or skipping meals, to manage their weight."""""""" The economic and social burdeps of eating disorders are substantial.(8,9) Medical complications are extremely common and the rate of mortality is very high. In fact, welldesigned studies have found a mortality rate in anorexia nervosa of over one half percent per year(10,11) and recent evidence documents elevated mortality in other eating disorders as well.(12) Moreover, disordered eating may be important to our understanding of the causes, prevention, and treatment of obesity. For example, patterns of binge eating and night eating in obese individuals have been recognized for over 50 years(13) The phenomenon of binge eating has been a topic of increased interest and controversy over the last 15-20 years. In summary, disordered eating has a high prevalence rate, significant medical and psychosocial co-morbidities, and important implications for treating and preventing obesity. For these reasons, a Disordered Eating Behavior Core is a valuable component ofthe center.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK050456-17
Application #
8447660
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
17
Fiscal Year
2012
Total Cost
$121,012
Indirect Cost
$32,540
Name
University of Minnesota Twin Cities
Department
Type
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
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S√łndergaard, Esben; Espinosa De Ycaza, Ana Elena; Morgan-Bathke, Maria et al. (2017) How to Measure Adipose Tissue Insulin Sensitivity. J Clin Endocrinol Metab 102:1193-1199
Jahansouz, C; Xu, H; Hertzel, A V et al. (2017) Partitioning of adipose lipid metabolism by altered expression and function of PPAR isoforms after bariatric surgery. Int J Obes (Lond) :
Hippen, K L; O'Connor, R S; Lemire, A M et al. (2017) In Vitro Induction of Human Regulatory T Cells Using Conditions of Low Tryptophan Plus Kynurenines. Am J Transplant 17:3098-3113

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