The Clinical Science Research Core (CSRC) enhances and facilitates nutrition/obesity-related clinical translational research by assisting investigators in conducting studies in human subjects through the operation of two sub-cores. The Clinical Studies Performance sub-core facilitates clinical research by assistance with: i) subject recruitment, ii) planning and performance of clinical studies, iii) collection of fat and muscle tissue samples, iv) exercise testing, v) lifestyle intervention, vi) whole-body and regional body composition assessments (DEXA, MRI, MRS), vii) indirect calorimetry, and viii) assessment of cardiovascular structure and function. The Metabolic Kinetics sub-core provides comprehensive state-of the- art stable isotope labeled tracer and non-tracer applications to study diverse areas of metabolic function (production/synthesis and catabolic rates;insulin sensitivity, beta-cell function). In addition, the CSRC provides training for investigators, their staff, and research fellows in these areas of clinical research, both in the form of one-on-one hands-on instruction as well as through seminars and lecture series. Combining these services within one Core provides a cohesive organizational structure that facilitates the performance of complex clinical research studies, fosters interdisciplinary collaborations between NORC investigators, and reduces the barriers for basic scientists and young investigators who wish to conduct clinical research.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK056341-14
Application #
8640146
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
14
Fiscal Year
2014
Total Cost
$325,459
Indirect Cost
$111,341
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
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