The goal of the BMAC is to offer a comprehensive range of MS analyses for the structural characterization and quantification of nutrition-related biomolecules for NORC investigators. The predominant BMAC objective is to provide means for NORC investigators to gain maximum benefit from the power of MS with a focus on three areas of need: 1) To apply the sensitivity and specificity of MS to detect and quantify low abundance biomolecules;2) To develop innovative MS techniques for detection and structural characterization of nutritionor obesity-related biomolecules;and 3) To provide MS training for students and fellows in nutrition or obesity research. Because MS analyses are labor-intensive and require specialized skills, it is often more economical and practical for BMAC Core staff to perform MS analyses. In cases where sustained demand for analyses or development of analytical techniques is anticipated, members of investigators'laboratories are trained to perform appropriate MS procedures.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK056341-14
Application #
8640150
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
14
Fiscal Year
2014
Total Cost
$80,788
Indirect Cost
$27,638
Name
Washington University
Department
Type
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Lucey, Brendan P; Mawuenyega, Kwasi G; Patterson, Bruce W et al. (2016) Associations Between β-Amyloid Kinetics and the β-Amyloid Diurnal Pattern in the Central Nervous System. JAMA Neurol :
Piggott, Damani A; Erlandson, Kristine M; Yarasheski, Kevin E (2016) Frailty in HIV: Epidemiology, Biology, Measurement, Interventions, and Research Needs. Curr HIV/AIDS Rep 13:340-348
Magkos, Faidon; Fraterrigo, Gemma; Yoshino, Jun et al. (2016) Effects of Moderate and Subsequent Progressive Weight Loss on Metabolic Function and Adipose Tissue Biology in Humans with Obesity. Cell Metab 23:591-601
G Clifton, Rebecca; Evans, Mary; Cahill, Alison G et al. (2016) Design of lifestyle intervention trials to prevent excessive gestational weight gain in women with overweight or obesity. Obesity (Silver Spring) 24:305-13
Saben, Jessica L; Boudoures, Anna L; Asghar, Zeenat et al. (2016) Maternal Metabolic Syndrome Programs Mitochondrial Dysfunction via Germline Changes across Three Generations. Cell Rep 16:1-8
Armamento-Villareal, R; Aguirre, L E; Qualls, C et al. (2016) Effect of Lifestyle Intervention on the Hormonal Profile of Frail, Obese Older Men. J Nutr Health Aging 20:334-40
Martínez-Montañés, Fernando; Lone, Museer A; Hsu, Fong-Fu et al. (2016) Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether. J Lipid Res 57:2040-2050
Fabbrini, Elisa; Tiemann Luecking, Courtney; Love-Gregory, Latisha et al. (2016) Physiological Mechanisms of Weight Gain-Induced Steatosis in People With Obesity. Gastroenterology 150:79-81.e2
Chondronikola, M; Harris, L L S; Klein, S (2016) Bariatric surgery and type 2 diabetes: are there weight loss-independent therapeutic effects of upper gastrointestinal bypass? J Intern Med 280:476-486
Yoshino, Jun; Smith, Gordon I; Kelly, Shannon C et al. (2016) Effect of dietary n-3 PUFA supplementation on the muscle transcriptome in older adults. Physiol Rep 4:

Showing the most recent 10 out of 1194 publications