The Nutritional Biochemistry and Metabolomics Core facility provides investigators performing nutritionally related research with standardized and quality controlled biochemical assays, with the ability to learn molecular biology techniques or have the core process samples for molecular biological assays, and with access to equipment (e.g. flow cytometry, icycler, spectrophotometer, Cobas mira system, gel documentation, fluorescent and light microscopy with digital camera. ELISA reader and plate washer, ultracentrifuge, X24 extracellular flux analyzer). Many of our users are nutritional epidemiologists or nutritional interventionists who do not have wet lab space, yet they require biomarker measures (often routine assays) for their studies and therefore, need a Core facility to analyze their samples. Biomarker consultation is also a core strength. Core personnel work with investigators to determine the appropriate biomarkers for the study question as well as appropriate sample handling. In addition. Core Personnel provide expertise in data interpretation for users.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK056350-13
Application #
8665738
Study Section
Special Emphasis Panel (ZDK1-GRB-2 (J2))
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
13
Fiscal Year
2013
Total Cost
$18,395
Indirect Cost
$5,661
Name
University of North Carolina Chapel Hill
Department
Type
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Xue, Jing; Schoenrock, Sarah A; Valdar, William et al. (2016) Maternal vitamin D depletion alters DNA methylation at imprinted loci in multiple generations. Clin Epigenetics 8:107
Qin, Bo; Viera, Anthony J; Muntner, Paul et al. (2016) Visit-to-Visit Variability in Blood Pressure Is Related to Late-Life Cognitive Decline. Hypertension 68:106-13
Qin, Yuanyuan; Sundaram, Sneha; Essaid, Luma et al. (2016) Weight loss reduces basal-like breast cancer through kinome reprogramming. Cancer Cell Int 16:26
Fry, Constance L; Naugle Jr, Thomas C; Cole, Shelley A et al. (2016) The Latino Eyelid: Anthropometric Analysis of a Spectrum of Findings. Ophthal Plast Reconstr Surg :
Zwart, Sara R; Gregory, Jesse F; Zeisel, Steven H et al. (2016) Genotype, B-vitamin status, and androgens affect spaceflight-induced ophthalmic changes. FASEB J 30:141-8
Batis, Carolina; Mendez, Michelle A; Gordon-Larsen, Penny et al. (2016) Using both principal component analysis and reduced rank regression to study dietary patterns and diabetes in Chinese adults. Public Health Nutr 19:195-203
Huang, Madelyn C; Douillet, Christelle; Su, Mingming et al. (2016) Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure. Arch Toxicol :
Huang, Chi; Liu, Chao-Jie; Pan, Xiong-Fei et al. (2016) Correlates of unequal access to preventive care in China: a multilevel analysis of national data from the 2011 China Health and Nutrition Survey. BMC Health Serv Res 16:177
Zhang, Ji; Xue, Hong; Cheng, Xi et al. (2016) Influence of proximities to food establishments on body mass index among children in China. Asia Pac J Clin Nutr 25:134-41
Nilsson, Torbjörn K; Hurtig-Wennlöf, Anita; Sjöström, Michael et al. (2016) Plasma 1-carbon metabolites and academic achievement in 15-yr-old adolescents. FASEB J 30:1683-8

Showing the most recent 10 out of 748 publications