Overall Component The overarching theme of the Nutrition Obesity Research Center (NORC) at the University of North Carolina at Chapel Hill is Trans-Disciplinary Nutrition Research: From Molecules to Public Health. The NORC adapts and translates expertise in community/population-based and clinical studies to facilitate the transfer of ideas and information to the laboratory, while at the same time helping to translate ideas from the laboratory into new hypotheses for studies at the clinical and community level. We propose an Administrative Core and five Scientific Cores: Diet and Physical Activity in Human Populations (DPAC), Communication for Health Applications and Interventions (CHAI), Metabolic Molecular Phenotyping (MMP) and Animal Metabolism Phenotyping (AMP), all of which are ongoing successful cores already providing exceptional services to NORC members. The Nutrigenetics Core (NGx) is a new developmental core that will get seed funding to develop services that will help public health and other researchers access nutrigenetics methods for use in their research. Our record of success during the last funding period is substantial. NORC activities have resulted in significant increases in the number and productivity of nutrition and obesity investigators at UNC, the funding for nutrition and obesity research, and the understanding of the importance of nutrition and obesity among researchers, clinicians, and the general public. The NORC has 130 member scientists from 36 different departments and divisions of UNC. They have exceptional research funding, having been awarded $179.8 million in nutrition and obesity grants during the last five years ($40.6 million in 2015 alone (first quarter)). Of this total, 91% of the funding was from federal grants ($163.3 million, NIH, USDA, CDC, DOD) with $41.7 million from the NIDDK. Our research base members have an exceptional publication record; with 859 peer- reviewed publications that are directly related to the support they received from the NORC.

Public Health Relevance

The University of North Carolina Nutrition Obesity Research Center (UNC NORC) focuses on Trans- Disciplinary Nutrition Research: From Molecules to Public Health. We propose an Administrative Core and five Scientific Core Facilities: 'Diet and Physical Activity in Human Populations (DPAC),' 'Nutrition Communication for Health Applications and Interventions (CHAI),' 'Metabolic Molecular Phenotyping (MMP)', 'Animal Metabolism Phenotyping (AMP) and Nutrigenetics (NGx)

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
2P30DK056350-16
Application #
9094767
Study Section
Special Emphasis Panel (ZDK1)
Program Officer
Evans, Mary
Project Start
1999-09-30
Project End
2021-03-31
Budget Start
2016-04-15
Budget End
2017-03-31
Support Year
16
Fiscal Year
2016
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Nutrition
Type
Schools of Public Health
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Smith-Ryan, Abbie E; Blue, Malia N M; Trexler, Eric T et al. (2018) Utility of ultrasound for body fat assessment: validity and reliability compared to a multicompartment criterion. Clin Physiol Funct Imaging 38:220-226
Blue, R Eric; Curry, Ennessa G; Engels, Nichlas M et al. (2018) How alternative splicing affects membrane-trafficking dynamics. J Cell Sci 131:
Birken, Sarah A; Rohweder, Catherine L; Powell, Byron J et al. (2018) T-CaST: an implementation theory comparison and selection tool. Implement Sci 13:143
Buglak, Nicholas E; Batrakova, Elena V; Mota, Roberto et al. (2018) Insights on Localized and Systemic Delivery of Redox-Based Therapeutics. Oxid Med Cell Longev 2018:2468457
Dover, E Nicole; Patel, Naishal Y; St├Żblo, Miroslav (2018) Impact of in vitro heavy metal exposure on pancreatic ?-cell function. Toxicol Lett 299:137-144
Branca, Rosa T; McCallister, Andrew; Yuan, Hong et al. (2018) Accurate quantification of brown adipose tissue mass by xenon-enhanced computed tomography. Proc Natl Acad Sci U S A 115:174-179
Grummon, Anna H; Taillie, Lindsey Smith (2018) Supplemental Nutrition Assistance Program participation and racial/ethnic disparities in food and beverage purchases. Public Health Nutr 21:3377-3385
Zhang, Jiguo; Wang, Huijun; Wang, Zhihong et al. (2018) Prevalence and stabilizing trends in overweight and obesity among children and adolescents in China, 2011-2015. BMC Public Health 18:571
Xu, Xiaoyue; Parker, Deborah; Shi, Zumin et al. (2018) Dietary Pattern, Hypertension and Cognitive Function in an Older Population: 10-Year Longitudinal Survey. Front Public Health 6:201
McClain, Kathleen M; Bradshaw, Patrick T; Khankari, Nikhil K et al. (2018) Fish/shellfish intake and the risk of head and neck cancer. Eur J Cancer Prev :

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