Overall Component The overarching theme of the Nutrition Obesity Research Center (NORC) at the University of North Carolina at Chapel Hill is Trans-Disciplinary Nutrition Research: From Molecules to Public Health. The NORC adapts and translates expertise in community/population-based and clinical studies to facilitate the transfer of ideas and information to the laboratory, while at the same time helping to translate ideas from the laboratory into new hypotheses for studies at the clinical and community level. We propose an Administrative Core and five Scientific Cores: Diet and Physical Activity in Human Populations (DPAC), Communication for Health Applications and Interventions (CHAI), Metabolic Molecular Phenotyping (MMP) and Animal Metabolism Phenotyping (AMP), all of which are ongoing successful cores already providing exceptional services to NORC members. The Nutrigenetics Core (NGx) is a new developmental core that will get seed funding to develop services that will help public health and other researchers access nutrigenetics methods for use in their research. Our record of success during the last funding period is substantial. NORC activities have resulted in significant increases in the number and productivity of nutrition and obesity investigators at UNC, the funding for nutrition and obesity research, and the understanding of the importance of nutrition and obesity among researchers, clinicians, and the general public. The NORC has 130 member scientists from 36 different departments and divisions of UNC. They have exceptional research funding, having been awarded $179.8 million in nutrition and obesity grants during the last five years ($40.6 million in 2015 alone (first quarter)). Of this total, 91% of the funding was from federal grants ($163.3 million, NIH, USDA, CDC, DOD) with $41.7 million from the NIDDK. Our research base members have an exceptional publication record; with 859 peer- reviewed publications that are directly related to the support they received from the NORC.

Public Health Relevance

The University of North Carolina Nutrition Obesity Research Center (UNC NORC) focuses on Trans- Disciplinary Nutrition Research: From Molecules to Public Health. We propose an Administrative Core and five Scientific Core Facilities: 'Diet and Physical Activity in Human Populations (DPAC),' 'Nutrition Communication for Health Applications and Interventions (CHAI),' 'Metabolic Molecular Phenotyping (MMP)', 'Animal Metabolism Phenotyping (AMP) and Nutrigenetics (NGx)

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Center Core Grants (P30)
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Special Emphasis Panel (ZDK1)
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Evans, Mary
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University of North Carolina Chapel Hill
Schools of Public Health
Chapel Hill
United States
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Zhang, Le; Burant, Alex; McCallister, Andrew et al. (2017) Accurate MR thermometry by hyperpolarized 129 Xe. Magn Reson Med 78:1070-1079
Rummo, Pasquale E; Guilkey, David K; Ng, Shu Wen et al. (2017) Does unmeasured confounding influence associations between the retail food environment and body mass index over time? The Coronary Artery Risk Development in Young Adults (CARDIA) study. Int J Epidemiol 46:1456-1464
Dearth-Wesley, Tracy; Howard, Annie Green; Wang, Huijun et al. (2017) Trends in domain-specific physical activity and sedentary behaviors among Chinese school children, 2004-2011. Int J Behav Nutr Phys Act 14:141
Tian, Xu; Ding, Caicui; Shen, Chong et al. (2017) Does Parental Migration Have Negative Impact on the Growth of Left-Behind Children?-New Evidence from Longitudinal Data in Rural China. Int J Environ Res Public Health 14:
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Rummo, Pasquale E; Guilkey, David K; Ng, Shu Wen et al. (2017) Beyond Supermarkets: Food Outlet Location Selection in Four U.S. Cities Over Time. Am J Prev Med 52:300-310
Shapiro, Allison L B; Ringham, Brandy M; Glueck, Deborah H et al. (2017) Infant Adiposity is Independently Associated with a Maternal High Fat Diet but not Related to Niacin Intake: The Healthy Start Study. Matern Child Health J 21:1662-1668
Styner, Maya; Pagnotti, Gabriel M; McGrath, Cody et al. (2017) Exercise Decreases Marrow Adipose Tissue Through ß-Oxidation in Obese Running Mice. J Bone Miner Res 32:1692-1702
Ahmed, Z; Farjana, Y (2017) It is Time to Obligate the Warning Messages on Junk Food Packages and Advertisements: A Step to live long. Diabetes Obes Int J 2:
Clauss, Sebastian; Scherr, Johannes; Hanley, Alan et al. (2017) Impact of polyphenols on physiological stress and cardiac burden in marathon runners - results from a substudy of the BeMaGIC study. Appl Physiol Nutr Metab 42:523-528

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