The Administrative Core of the UCSF Diabetes and Endocrinology Research Center (DERC) provides leadership, infrastructure, administrative support, and advice and oversight to the other components and members of the DERC. The Center Director (or when absent, the Associate Director) provides day-to-day leadership and interactions with the Directors of the Programs and Cores that constitute the DERC, administrative staff and DERC membership. The Center Director, together with the Directors of the four Research Programs (in Islet Biology, Obesity &Metabolism, Autoimmunity &Inflammation, and Translation) constitute the Executive Committee. The Executive Committee meets quarterly and, when necessary on an ad hoc basis, to set long-range goals in consultation with the Directors of the Pilot &Feasibility and Enrichment Programs and with a Core Coordinating Committee consisting of all four Core Directors and an overall Director of Cores. The Core Coordinating Committee discusses issues and solutions related to Core operations and the provision of Core services to the DERC membership. The Executive Committee also evaluates the external reviews from the Pilot &Feasibility applications and ensures continuing mentorship and advice to Pilot &Feasibility grant recipients. The Executive Committee meets annually with an External Advisory Committee which provides valuable insights into the scientific and operational directions of the DERC. A biannual meeting of the Executive Committee with an Internal Advisory Committee, which consists of institutional leaders with interests in DERC-related research, provides valuable insights about DERC progress in relationship with University goals. The DERC interfaces with its membership, the NIDDK, other NIH Diabetes Centers, and the lay community through this organizational structure and through outreach programs including the Enrichment Program, the Pilot &Feasibility grant program and its web site and other informational materials.

Public Health Relevance

The Objectives of the UCSF DERC are to provide an organizational structure that fosters research collaborations and interactions that accelerate the pace of diabetes research. The Administrative component is charged with providing leadership that responds nimbly to its constituency and that ensures all activities are coordinated towards common goals.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK063720-10
Application #
8640153
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
10
Fiscal Year
2014
Total Cost
$1,313,250
Indirect Cost
$463,250
Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Khan, Imran S; Mouchess, Maria L; Zhu, Meng-Lei et al. (2014) Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance. J Exp Med 211:761-8
von Figura, Guido; Fukuda, Akihisa; Roy, Nilotpal et al. (2014) The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma. Nat Cell Biol 16:255-67
Schaufele, Fred (2014) Maximizing the quantitative accuracy and reproducibility of Forster resonance energy transfer measurement for screening by high throughput widefield microscopy. Methods 66:188-99
Ghosh, Rajarshi; Wang, Likun; Wang, Eric S et al. (2014) Allosteric inhibition of the IRE1? RNase preserves cell viability and function during endoplasmic reticulum stress. Cell 158:534-48
Lee, K; Nguyen, V; Lee, K-M et al. (2014) Attenuation of donor-reactive T cells allows effective control of allograft rejection using regulatory T cell therapy. Am J Transplant 14:27-38
Ni, Wei; Watts, Stephanie W; Ng, Michael et al. (2014) Elimination of vitamin D receptor in vascular endothelial cells alters vascular function. Hypertension 64:1290-8
Maly, Dustin J; Papa, Feroz R (2014) Druggable sensors of the unfolded protein response. Nat Chem Biol 10:892-901
Kim, Mee J; Oksenberg, Nir; Hoffmann, Thomas J et al. (2014) Functional characterization of SIM1-associated enhancers. Hum Mol Genet 23:1700-8
Baeyens, Luc; Lemper, Marie; Leuckx, Gunter et al. (2014) Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nat Biotechnol 32:76-83
Khan, Imran S; Taniguchi, Ruth T; Fasano, Kayla J et al. (2014) Canonical microRNAs in thymic epithelial cells promote central tolerance. Eur J Immunol 44:1313-9

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