The principal goal of the Human Phenotyping Core is to provide high quality, innovative and state-of-the-art clinical phenotypes for NORC members The current objectives of the Core are to: a) Complete testing and validation of the procedures currently in development. b) Consolidate and finalize quality control procedures. In addition, we plan to maintain and consolidate our current quality control procedures, and strive to provide efficient and high quality services to NORC users. A major goal of the Human Phenotyping Core is to complete QC sheets (see Appendix VIM) for each phenotype. c) Develop fMRI - the major initiative of the Human Phenotyping Sub-Core in the next cycle will be to develop and validate functional Magnetic Resonance Imaging (fMRI) procedures. Dr. Steven Smith will devote 10 % of his time to this task and transition it to Dr. Ravussin and an Investigator with Physics Science expertise to be named.

National Institute of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Center Core Grants (P30)
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Special Emphasis Panel (ZDK1-GRB-2 (M2))
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Lsu Pennington Biomedical Research Center
Baton Rouge
United States
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White, Ursula A; Fitch, Mark D; Beyl, Robbie A et al. (2017) Association of In Vivo Adipose Tissue Cellular Kinetics With Markers of Metabolic Health in Humans. J Clin Endocrinol Metab 102:2171-2178
Sparks, Lauren M; Redman, Leanne M; Conley, Kevin E et al. (2017) Effects of 12 Months of Caloric Restriction on Muscle Mitochondrial Function in Healthy Individuals. J Clin Endocrinol Metab 102:111-121
Broskey, Nicholas T; Klempel, Monica C; Gilmore, L Anne et al. (2017) Assessing Energy Requirements in Women With Polycystic Ovary Syndrome: A Comparison Against Doubly Labeled Water. J Clin Endocrinol Metab 102:1951-1959
Staiano, A E; Marker, A M; Beyl, R A et al. (2017) A randomized controlled trial of dance exergaming for exercise training in overweight and obese adolescent girls. Pediatr Obes 12:120-128
Hill, Cristal M; Laeger, Thomas; Albarado, Diana C et al. (2017) Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints. Sci Rep 7:8209
Chang, Ji Suk; Ha, Kyoungsoo (2017) An unexpected role for the transcriptional coactivator isoform NT-PGC-1? in the regulation of mitochondrial respiration in brown adipocytes. J Biol Chem 292:9958-9966
Peterson, Courtney M; Orooji, Mahdi; Johnson, Deanna N et al. (2017) Brown adipose tissue does not seem to mediate metabolic adaptation to overfeeding in men. Obesity (Silver Spring) 25:502-505
Lee, J H; Zhang, Y; Zhao, Z et al. (2017) Intracellular ATP in balance of pro- and anti-inflammatory cytokines in adipose tissue with and without tissue expansion. Int J Obes (Lond) 41:645-651
Forney, Laura A; Wanders, Desiree; Stone, Kirsten P et al. (2017) Concentration-dependent linkage of dietary methionine restriction to the components of its metabolic phenotype. Obesity (Silver Spring) 25:730-738
Covington, Jeffrey D; Johannsen, Darcy L; Coen, Paul M et al. (2017) Intramyocellular Lipid Droplet Size Rather Than Total Lipid Content is Related to Insulin Sensitivity After 8 Weeks of Overfeeding. Obesity (Silver Spring) 25:2079-2087

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