Abstract

The principal goal of the Human Phenotyping Core is to provide high quality, innovative and state-of-the-art clinical phenotypes for NORC members The current objectives of the Core are to: a) Complete testing and validation of the procedures currently in development. b) Consolidate and finalize quality control procedures. In addition, we plan to maintain and consolidate our current quality control procedures, and strive to provide efficient and high quality services to NORC users. A major goal of the Human Phenotyping Core is to complete QC sheets (see Appendix VIM) for each phenotype. c) Develop fMRI - the major initiative of the Human Phenotyping Sub-Core in the next cycle will be to develop and validate functional Magnetic Resonance Imaging (fMRI) procedures. Dr. Steven Smith will devote 10 % of his time to this task and transition it to Dr. Ravussin and an Investigator with Physics Science expertise to be named.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK072476-08
Application #
8565052
Study Section
Special Emphasis Panel (ZDK1-GRB-2 (M2))
Project Start
2005-09-15
Project End
2015-08-31
Budget Start
2012-09-01
Budget End
2013-08-31
Support Year
8
Fiscal Year
2012
Total Cost
$245,038
Indirect Cost
$79,472

  Institution

Name
Lsu Pennington Biomedical Research Center
Department
Type
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808

  Publications

Redman, Leanne M; Smith, Steven R; Burton, Jeffrey H et al. (2018) Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Support the Rate of Living and Oxidative Damage Theories of Aging. Cell Metab 27:805-815.e4
Nicklas, Theresa; Islam, Noemi G; Saab, Rabab et al. (2018) Validity of a Digital Diet Estimation Method for Use with Preschool Children. J Acad Nutr Diet 118:252-260
King, Jill L; Fearnbach, S Nicole; Ramakrishnapillai, Sreekrishna et al. (2018) Perceptual Characterization of the Macronutrient Picture System (MaPS) for Food Image fMRI. Front Psychol 9:17
Roe, Brian E; Apolzan, John W; Qi, Danyi et al. (2018) Plate waste of adults in the United States measured in free-living conditions. PLoS One 13:e0191813
Bruce-Keller, Annadora J; Salbaum, J Michael; Berthoud, Hans-Rudolf (2018) Harnessing Gut Microbes for Mental Health: Getting From Here to There. Biol Psychiatry 83:214-223
Yu, Sangho; Münzberg, Heike (2018) Testing Effects of Chronic Chemogenetic Neuronal Stimulation on Energy Balance by Indirect Calorimetry. Bio Protoc 8:
Elbers, Jean P; Brown, Mary B; Taylor, Sabrina S (2018) Identifying genome-wide immune gene variation underlying infectious disease in wildlife populations - a next generation sequencing approach in the gopher tortoise. BMC Genomics 19:64
Kaviani, Sepideh; Schoeller, Dale A; Ravussin, Eric et al. (2018) Determining the Accuracy and Reliability of Indirect Calorimeters Utilizing the Methanol Combustion Technique. Nutr Clin Pract 33:206-216
Peterson, Courtney M; Beyl, Robbie A; Marlatt, Kara L et al. (2018) Effect of 12 wk of resistant starch supplementation on cardiometabolic risk factors in adults with prediabetes: a randomized controlled trial. Am J Clin Nutr 108:492-501
Graf, Brittany L; Zhang, Li; Corradini, Maria G et al. (2018) Physicochemical differences between malanga (Xanthosoma sagittifolium) and potato (Solanum tuberosum) tubers are associated with differential effects on the gut microbiome. J Funct Foods 45:268-276

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