The Pennington Biomedical Research Center CNRU (to be called NORC beginning 2010) was first funded by the NIDDK in September 2005, with Dr. Eric Ravussin as Director and Dr. Donna Ryan as Associate Director. The NORC at Pennington has as its mission the advancement of nutrition and obesity research, broadly defined, as well as providing special emphasis within a thematic area. The chosen theme of the NORC is "Nutritional Programming: Environmental and Molecular Interactions". This focus is based on emerging interests in epigenetic phenomena such as how environmental events in prenatal and early post-natal life can influence (through biologic mechanisms such as by gene methylations and demethylations) the risk for the development of obesity and metabolic syndrome in later adulthood. Without a doubt, the theme chosen five years ago was prescient, as there continues to be ever growing interest in epigenetic drivers which can impact chronic diseases in adulthood, primarily through mediation of the different facets of the metabolic syndrome and the chronic impairments associated with aging. Overview of the Organization of the NORC: To achieve our aim of promoting high quality research and facilitating multi-disciplinary collaboration among investigators involved in nutrition and obesity research, the organization of the NORC is designed to be integrated into the structure of the host institution, Pennington Biomedical Research Center. The structure of the original CNRU included the following four Cores: Administrative Core led by Drs. Eric Ravussin and Donna Ryan, Human Phenotyping Core led by Drs. Steve Smith and Donald Williamson, Molecular Mechanisms Core led by Drs. Les Kozak, Jeff Gimble and Tom Gettys and Animal Models and Phenotyping Core led by Drs. Andrew Butler and Randy Mynatt. The organizational structure and function of the NORC is described later in greater detail. Note that for this renewal the Human Phenotyping Core is now led by Dr. William Cefalu, the Molecular Mechanisms Core by Dr. Les Kozak with Dr. David Burk as Associate Director and the Animal Models and Phenotyping Core now led by Dr. Randy Mynatt with Dr. Don Ingram as Associate Director.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK072476-10
Application #
8726952
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
10
Fiscal Year
2014
Total Cost
$309,894
Indirect Cost
$100,506
Name
Lsu Pennington Biomedical Research Center
Department
Type
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808
Correa, John B; Apolzan, John W; Shepard, Desti N et al. (2016) Evaluation of the ability of three physical activity monitors to predict weight change and estimate energy expenditure. Appl Physiol Nutr Metab 41:758-66
Yu, Sangho; Qualls-Creekmore, Emily; Rezai-Zadeh, Kavon et al. (2016) Glutamatergic Preoptic Area Neurons That Express Leptin Receptors Drive Temperature-Dependent Body Weight Homeostasis. J Neurosci 36:5034-46
Covington, Jeffrey D; Tam, Charmaine S; Bajpeyi, Sudip et al. (2016) Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation. Med Sci Sports Exerc 48:384-90
Na, Ha-Na; Hegde, Vijay; Dubuisson, Olga et al. (2016) E4orf1 Enhances Glucose Uptake Independent of Proximal Insulin Signaling. PLoS One 11:e0161275
Zhang, Yong; Zhao, Zhiyun; Ke, Bilun et al. (2016) Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function. PLoS One 11:e0150454
Carvajal-Aldaz, Diana G; Guice, Justin L; Page, Ryan C et al. (2016) Simultaneous delivery of antibiotics neomycin and ampicillin in drinking water inhibits fermentation of resistant starch in rats. Mol Nutr Food Res :
Dasuri, Kalavathi; Zhang, Le; Kim, Sun O K Fernandez et al. (2016) Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain. Biochim Biophys Acta 1862:274-83
Apolzan, John W; Myers, Candice A; Cowley, Amanda D et al. (2016) Examination of the reliability and validity of the Mindful Eating Questionnaire in pregnant women. Appetite 100:142-51
Rundle, Andrew G; Heymsfield, Steven B (2016) Can Walkable Urban Design Play a Role in Reducing the Incidence of Obesity-Related Conditions? JAMA 315:2175-7
Covington, Jeffrey D; Tam, Charmaine S; Pasarica, Magdalena et al. (2016) Higher circulating leukocytes in women with PCOS is reversed by aerobic exercise. Biochimie 124:27-33

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