The principal goal of the Human Phenotyping Core is to provide high quality, innovative and state-of-the-art clinical phenotypes for NORC members The current objectives of the Core are to: a) Complete testing and validation of the procedures currently in development. b) Consolidate and finalize quality control procedures. In addition, we plan to maintain and consolidate our current quality control procedures, and strive to provide efficient and high quality services to NORC users. A major goal of the Human Phenotyping Core is to complete QC sheets (see Appendix VIM) for each phenotype. c) Develop fMRI - the major initiative of the Human Phenotyping Sub-Core in the next cycle will be to develop and validate functional Magnetic Resonance Imaging (fMRI) procedures. Dr. Steven Smith will devote 10 % of his time to this task and transition it to Dr. Ravussin and an Investigator with Physics Science expertise to be named.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK072476-10
Application #
8726953
Study Section
Special Emphasis Panel (ZDK1-GRB-2)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
10
Fiscal Year
2014
Total Cost
$243,630
Indirect Cost
$79,015
Name
Lsu Pennington Biomedical Research Center
Department
Type
DUNS #
611012324
City
Baton Rouge
State
LA
Country
United States
Zip Code
70808
Myers, Candice A; Slack, Tim; Martin, Corby K et al. (2015) Regional disparities in obesity prevalence in the United States: A spatial regime analysis. Obesity (Silver Spring) 23:481-7
Gilmore, L Anne; Redman, Leanne M (2015) Weight gain in pregnancy and application of the 2009 IOM guidelines: toward a uniform approach. Obesity (Silver Spring) 23:507-11
Galgani, Jose E; Mizgier, Maria L; Mari, Andrea et al. (2014) Relationship between whole-body macronutrient oxidative partitioning and pancreatic insulin secretion/?-cell function in non-diabetic humans. Metabolism 63:1426-31
Lackey, Denise E; Burk, David H; Ali, Mohamed R et al. (2014) Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity. Am J Physiol Endocrinol Metab 306:E233-46
Ghosh, Sujoy; Wanders, Desiree; Stone, Kirsten P et al. (2014) A systems biology analysis of the unique and overlapping transcriptional responses to caloric restriction and dietary methionine restriction in rats. FASEB J 28:2577-90
Frost, Elizabeth A; Redman, Leanne M; de Jonge, Lilian et al. (2014) Interaction between dietary fat and exercise on excess postexercise oxygen consumption. Am J Physiol Endocrinol Metab 306:E1093-8
St-Onge, Marie-Pierre; Shechter, Ari; Shlisky, Julie et al. (2014) Fasting plasma adropin concentrations correlate with fat consumption in human females. Obesity (Silver Spring) 22:1056-63
Johannsen, Darcy L; Tchoukalova, Yourka; Tam, Charmaine S et al. (2014) Effect of 8 weeks of overfeeding on ectopic fat deposition and insulin sensitivity: testing the "adipose tissue expandability" hypothesis. Diabetes Care 37:2789-97
Stone, Kirsten P; Wanders, Desiree; Orgeron, Manda et al. (2014) Mechanisms of increased in vivo insulin sensitivity by dietary methionine restriction in mice. Diabetes 63:3721-33
Kirk-Ballard, Heather; Kilroy, Gail; Day, Britton C et al. (2014) An ethanolic extract of Artemisia dracunculus L. regulates gene expression of ubiquitin-proteasome system enzymes in skeletal muscle: potential role in the treatment of sarcopenic obesity. Nutrition 30:S21-5

Showing the most recent 10 out of 332 publications