Public Health Relevance

The DDBTRCC Translational Research Enhancement Core (Core D) has as its goal to make translating basic research findings made by the Core Center Research Base and other JHUSOM investigators easier and more efficient to achieve by investing in a Core in which the clinical data are recorded and specimens are uniformly banked

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK089502-02
Application #
8460707
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
2
Fiscal Year
2012
Total Cost
$145,775
Indirect Cost
$56,888
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Bettridge, John; Na, Chan Hyun; Pandey, Akhilesh et al. (2017) H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase. Proc Natl Acad Sci U S A 114:1904-1909
Blutt, Sarah E; Broughman, James R; Zou, Winnie et al. (2017) Gastrointestinal microphysiological systems. Exp Biol Med (Maywood) 242:1633-1642
Sunuwar, Laxmi; Asraf, Hila; Donowitz, Mark et al. (2017) The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl- absorption, via basolateral KCC1, and reduces fluid loss. Biochim Biophys Acta 1863:947-960
Jin, Peng; Wang, De-Zhi; Lyu, Chen-Xi et al. (2017) Mismatch Repair Protein hMLH1, but not hMSH2, Enhances Estrogen-Induced Apoptosis of Colon Cancer Cells. J Cancer 8:3232-3241
Anderson, Karen L; Page, Christopher; Swift, Mark F et al. (2017) Nano-scale actin-network characterization of fibroblast cells lacking functional Arp2/3 complex. J Struct Biol 197:312-321
Li, Ling; Piontek, Klaus; Ishida, Masaharu et al. (2017) Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model. Hepatology 65:501-514
Hosoda, Waki; Chianchiano, Peter; Griffin, James F et al. (2017) Genetic analyses of isolated high-grade pancreatic intraepithelial neoplasia (HG-PanIN) reveal paucity of alterations in TP53 and SMAD4. J Pathol 242:16-23
Cha, Boyoung; Yang, Jianbo; Singh, Varsha et al. (2017) PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs. J Biol Chem 292:8279-8290
Cil, Onur; Phuan, Puay-Wah; Son, Jung-Ho et al. (2017) Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation. Transl Res 182:14-26.e4
Becker, Laren; Nguyen, Linh; Gill, Jaspreet et al. (2017) Age-dependent shift in macrophage polarisation causes inflammation-mediated degeneration of enteric nervous system. Gut :

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