The Hopkins Digestive Diseases Basic and Translational Research Core Center Administrative Core is the glue which forms the structure of this Center by carrying out communications among the Center and Research Base investigators and Core Directors, performing budget management, serving as a repertoire for the software used by Center investigators and organizing all Center activities. In this way the Research Base of 50 investigataors (38 full members 12 associate members) are allowed to efficiently interact with the components ofthe Core Center, including the a) Administrative Core;b) 4 Scientific Cores-3 basic science [1) Proteomics;2) Imaging;3) Mouse Physiology] and a Translational Research Enhancement Core;c) Pilot Project Program;d) Enrichement Program which has multiple components. The specific functions ofthe Administrative Core include: a) Provide administrative and financial management ofthe Core Center;b) Provide monthly financial statements to Core Directors;c) Monitor use and perform charge-back for each Core 6x year;d) Inform Research Base weekly of work-in-progress meeting topic, lectures of interest around Hopkins, NIH funding opportunities, GI histology findings on mouse models studied by Research Base, Visiting Professor Program, Yearly Scientic Symposium, Yearly Retreat;e) Arrange a yearly meeting of External Scientific Advisory Committee, every other month meeting of Internal Executive Committee and Focus Groups, 6x year Visiting Professor Program, and yearly working group meetings for each Core;f) Organize and run yearly Research Base one day retreat;g) Organize and run yearly 1-2 day long Research Symposium;h) Organize and publish yearly Core Center newsletter;i) Assist in preparation of yearly DDBTRCC Progress Report for NIH;j) Prepare notes from yearly External Scientific Advisory Committee meeting;k) Organize and administer Pilot Project Program;1) Organize and administer Mini-Sabbatical Program;m) Help Research Base comply with JHUSOM, NIH, other governmental guidelines relating to research;n) Develop web page for Imaging and Mouse Physiology Cores;o) Help manage DDBTRCC service contracts;p) Help negotiate Core Center purchasing of equipment, service contracts, software; q) Serve as a repository for licenses for software purchased for Research Base and Core use.

Public Health Relevance

The Administrafive core is the glue which forms the structure of this Core Center by communicating Core Center activities to the Research Base investigators. Core Directors, and Core Center leadership, performing budget management and serving as the site of storage of the Core Center software that is made available to the Research Base.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Center Core Grants (P30)
Project #
5P30DK089502-04
Application #
8665919
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
4
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Bettridge, John; Na, Chan Hyun; Pandey, Akhilesh et al. (2017) H3K4me3 induces allosteric conformational changes in the DNA-binding and catalytic regions of the V(D)J recombinase. Proc Natl Acad Sci U S A 114:1904-1909
Blutt, Sarah E; Broughman, James R; Zou, Winnie et al. (2017) Gastrointestinal microphysiological systems. Exp Biol Med (Maywood) 242:1633-1642
Sunuwar, Laxmi; Asraf, Hila; Donowitz, Mark et al. (2017) The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl- absorption, via basolateral KCC1, and reduces fluid loss. Biochim Biophys Acta 1863:947-960
Jin, Peng; Wang, De-Zhi; Lyu, Chen-Xi et al. (2017) Mismatch Repair Protein hMLH1, but not hMSH2, Enhances Estrogen-Induced Apoptosis of Colon Cancer Cells. J Cancer 8:3232-3241
Anderson, Karen L; Page, Christopher; Swift, Mark F et al. (2017) Nano-scale actin-network characterization of fibroblast cells lacking functional Arp2/3 complex. J Struct Biol 197:312-321
Li, Ling; Piontek, Klaus; Ishida, Masaharu et al. (2017) Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model. Hepatology 65:501-514
Hosoda, Waki; Chianchiano, Peter; Griffin, James F et al. (2017) Genetic analyses of isolated high-grade pancreatic intraepithelial neoplasia (HG-PanIN) reveal paucity of alterations in TP53 and SMAD4. J Pathol 242:16-23
Cha, Boyoung; Yang, Jianbo; Singh, Varsha et al. (2017) PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs. J Biol Chem 292:8279-8290
Cil, Onur; Phuan, Puay-Wah; Son, Jung-Ho et al. (2017) Phenylquinoxalinone CFTR activator as potential prosecretory therapy for constipation. Transl Res 182:14-26.e4
Becker, Laren; Nguyen, Linh; Gill, Jaspreet et al. (2017) Age-dependent shift in macrophage polarisation causes inflammation-mediated degeneration of enteric nervous system. Gut :

Showing the most recent 10 out of 175 publications