PILOT PROGRAM ABSTRACT The Pilot Project Program is arguably the 'heart'of the Harvard-NIEHS Center. It encourages innovation and creativity, and provides a pathway for outstanding new investigators to enter environmental health research. It provides important support for new investigators to develop preliminary data to develop independent research projects and compete for independent funding for environmental health research. This program has encouraged new and creative research approaches and provide preliminary data and demonstrated feasibility for numerous career development and research project grants both from NIH and other funding sources. Pilot Project applications are solicited broadly from the Harvard academic community twice a year. Each application is reviewed for scientific merit by three experts (at least two outside the Center). The most sound applications are then ranked programmatically. All applicants are notified of funding decisions and given feedback within 6 weeks. Investigators needing resources for specific laboratory analyses may apply for Facility Access Funds with review and a decision within two days. The Center Pilot Program has been successful in attracting applications from across the spectrum of departments and disciplines in the Harvard Longwood Medical Area, and the Harvard academic community. In the first four years of the current Center grant, 29 pilot grant awards have resulted in 38 peer-reviewed publication plus 29 funded new grant awards. The Pilot Project program is a highly leveraged investment that facilitates the expansion of our Center research into critical areas of study. We continue to believe that pilot project funds are an extremely shrewd, high yield investment, which leads our Center research into important new areas of study.

Public Health Relevance

PILOT PROGRAM NARRATIVE Pilot Projects provide initial support to establish new lines of research, allow exploration of innovative new directions in environmental health sciences, provide a pathway for investigators from other disciplines to apply their expertise to environmental health research, and foster opportunities to fill in gaps in the Center research portfolio. The investment in Pilot Project has a high yield in innovation, new expertise, and collaborative initiative to address emerging environmental health issues.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Center Core Grants (P30)
Project #
Application #
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Harvard University
United States
Zip Code
Raz, Raanan; Weisskopf, Marc G; Davidovitch, Michael et al. (2015) Differences in autism spectrum disorders incidence by sub-populations in Israel 1992-2009: a total population study. J Autism Dev Disord 45:1062-9
Bollati, Valentina; Angelici, Laura; Rizzo, Giovanna et al. (2015) Microvesicle-associated microRNA expression is altered upon particulate matter exposure in healthy workers and in A549 cells. J Appl Toxicol 35:59-67
Mathews, Joel A; Williams, Alison S; Brand, Jeffrey D et al. (2014) ?? T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNF?. PLoS One 9:e97707
Luttmann-Gibson, Heike; Sarnat, Stefanie Ebelt; Suh, Helen H et al. (2014) Short-term effects of air pollution on oxygen saturation in a cohort of senior adults in Steubenville, Ohio. J Occup Environ Med 56:149-54
Wilker, Elissa H; Ljungman, Petter L; Rice, Mary B et al. (2014) Relation of long-term exposure to air pollution to brachial artery flow-mediated dilation and reactive hyperemia. Am J Cardiol 113:2057-63
Ma, Baoshan; Wilker, Elissa H; Willis-Owen, Saffron A G et al. (2014) Predicting DNA methylation level across human tissues. Nucleic Acids Res 42:3515-28
Wong, Jason Y Y; De Vivo, Immaculata; Lin, Xihong et al. (2014) The association between global DNA methylation and telomere length in a longitudinal study of boilermakers. Genet Epidemiol 38:254-64
Kasahara, David I; Kim, Hye Y; Mathews, Joel A et al. (2014) Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice. Am J Physiol Lung Cell Mol Physiol 306:L508-20
Chiu, Yueh-Hsiu Mathilda; Coull, Brent A; Sternthal, Michelle J et al. (2014) Effects of prenatal community violence and ambient air pollution on childhood wheeze in an urban population. J Allergy Clin Immunol 133:713-22.e4
Neophytou, Andreas M; Hart, Jaime E; Chang, Yan et al. (2014) Short-term traffic related exposures and biomarkers of nitro-PAH exposure and oxidative DNA damage. Toxics 2:377-390

Showing the most recent 10 out of 381 publications