PILOT PROGRAM ABSTRACT The Pilot Project Program is arguably the 'heart' of the Harvard-NIEHS Center. It encourages innovation and creativity, and provides a pathway for outstanding new investigators to enter environmental health research. It provides important support for new investigators to develop preliminary data to develop independent research projects and compete for independent funding for environmental health research. This program has encouraged new and creative research approaches and provide preliminary data and demonstrated feasibility for numerous career development and research project grants both from NIH and other funding sources. Pilot Project applications are solicited broadly from the Harvard academic community twice a year. Each application is reviewed for scientific merit by three experts (at least two outside the Center). The most sound applications are then ranked programmatically. All applicants are notified of funding decisions and given feedback within 6 weeks. Investigators needing resources for specific laboratory analyses may apply for Facility Access Funds with review and a decision within two days. The Center Pilot Program has been successful in attracting applications from across the spectrum of departments and disciplines in the Harvard Longwood Medical Area, and the Harvard academic community. In the first four years of the current Center grant, 29 pilot grant awards have resulted in 38 peer-reviewed publication plus 29 funded new grant awards. The Pilot Project program is a highly leveraged investment that facilitates the expansion of our Center research into critical areas of study. We continue to believe that pilot project funds are an extremely shrewd, high yield investment, which leads our Center research into important new areas of study.

Public Health Relevance

PILOT PROGRAM NARRATIVE Pilot Projects provide initial support to establish new lines of research, allow exploration of innovative new directions in environmental health sciences, provide a pathway for investigators from other disciplines to apply their expertise to environmental health research, and foster opportunities to fill in gaps in the Center research portfolio. The investment in Pilot Project has a high yield in innovation, new expertise, and collaborative initiative to address emerging environmental health issues.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES000002-53
Application #
9068125
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2016-04-01
Budget End
2017-03-31
Support Year
53
Fiscal Year
2016
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
Blomberg, Annelise J; Coull, Brent A; Jhun, Iny et al. (2018) Effect modification of ambient particle mortality by radon: a time series analysis in 108 U.S. cities. J Air Waste Manag Assoc :
Hopp, Stephanie; Dominici, Francesca; Bobb, Jennifer F (2018) Medical diagnoses of heat wave-related hospital admissions in older adults. Prev Med 110:81-85
Konduru, Nagarjun V; Damiani, Flavia; Stoilova-McPhie, Svetla et al. (2018) Nanoparticle Wettability Influences Nanoparticle-Phospholipid Interactions. Langmuir 34:6454-6461
Rodosthenous, Rodosthenis S; Kloog, Itai; Colicino, Elena et al. (2018) Extracellular vesicle-enriched microRNAs interact in the association between long-term particulate matter and blood pressure in elderly men. Environ Res 167:640-649
Rodan, Lance H; Hauptman, Marissa; D'Gama, Alissa M et al. (2018) Novel founder intronic variant in SLC39A14 in two families causing Manganism and potential treatment strategies. Mol Genet Metab 124:161-167
Woo, May K; Young, Elisabeth S; Mostofa, Md Golam et al. (2018) Lead in Air in Bangladesh: Exposure in a Rural Community with Elevated Blood Lead Concentrations among Young Children. Int J Environ Res Public Health 15:
Bose, Sonali; Rosa, Maria José; Mathilda Chiu, Yueh-Hsiu et al. (2018) Prenatal nitrate air pollution exposure and reduced child lung function: Timing and fetal sex effects. Environ Res 167:591-597
Wang, Qiyu; Yu, Jiujiu; Kadungure, Tatenda et al. (2018) ARMMs as a versatile platform for intracellular delivery of macromolecules. Nat Commun 9:960
Mostofsky, Elizabeth; Coull, Brent A; Mittleman, Murray A (2018) Analysis of Observational Self-matched Data to Examine Acute Triggers of Outcome Events with Abrupt Onset. Epidemiology 29:804-816
Bobb, Jennifer F; Claus Henn, Birgit; Valeri, Linda et al. (2018) Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression. Environ Health 17:67

Showing the most recent 10 out of 1142 publications