The mission of Aquatic Biomedical Models Facility Core (ABMFC) is to exploit the unique advantages of aquatic models to discover the environmental-biological interactions that influence the development of human disease. The ABMFC is dedicated to achieving these long-term goals: ? understand the full suite of environmental stressors that interact with and perturb the """"""""normal"""""""" developmental program, define the genes that play a role in increased susceptibility to environmental stressors, ? identify early and predictive biomarkers of human disease and discover novel therapeutic interventions, ? define the optimal fetal environment that reduces lifelong susceptibility to disease, and ? expand the use of chemical genetics to understand the mode of action of environmental stressors.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Center Core Grants (P30)
Project #
Application #
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Oregon State University
United States
Zip Code
Truong, Lisa; Bugel, Sean M; Chlebowski, Anna et al. (2016) Optimizing multi-dimensional high throughput screening using zebrafish. Reprod Toxicol 65:139-147
Vonnegut, Chris L; Shonkwiler, Airlia M; Zakharov, Lev N et al. (2016) Harnessing solid-state packing for selective detection of chloride in a macrocyclic anionophore. Chem Commun (Camb) 52:9506-9
He, Yunteng; Zhang, Jie; Kong, Wei (2016) Electron diffraction of CBr4 in superfluid helium droplets: A step towards single molecule diffraction. J Chem Phys 145:034307
Yang, Liping; Broderick, David; Campbell, Yan et al. (2016) Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies. Biochim Biophys Acta 1864:1667-1677
Teeguarden, Justin G; Tan, Yu-Mei; Edwards, Stephen W et al. (2016) Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework. Environ Sci Technol 50:4579-86
Seidl, Thomas L; Sundalam, Sunil K; McCullough, Brennen et al. (2016) Unsymmetrical Aryl(2,4,6-trimethoxyphenyl)iodonium Salts: One-Pot Synthesis, Scope, Stability, and Synthetic Studies. J Org Chem 81:1998-2009
Wattanasiritham, Ladda; Theerakulkait, Chockchai; Wickramasekara, Samanthi et al. (2016) Isolation and identification of antioxidant peptides from enzymatically hydrolyzed rice bran protein. Food Chem 192:156-62
Li, Feng; Huang, Chun-Hua; Xie, Lin-Na et al. (2016) An Exceptionally Facile Two-Step Structural Isomerization and Detoxication via a Water-Assisted Double Lossen Rearrangement. Sci Rep 6:39207
Hammers, Matthew D; Singh, Loveprit; Montoya, Leticia A et al. (2016) Synthesis of Amino-ADT Provides Access to Hydrolytically Stable Amide-Coupled Hydrogen Sulfide Releasing Drug Targets. Synlett 27:1349-1353
Serrill, Jeffrey D; Wan, Xuemei; Hau, Andrew M et al. (2016) Coibamide A, a natural lariat depsipeptide, inhibits VEGFA/VEGFR2 expression and suppresses tumor growth in glioblastoma xenografts. Invest New Drugs 34:24-40

Showing the most recent 10 out of 610 publications