PILOT PROJECT PROGRAM Director: Moon-shong (Eric) Tang, Ph.D. SIGNIFICANCE The four specific aims of this Pilot Project Program (PPP) are to: 1) promote the long-range research interests of the Center;2) foster collaboration between Center members and the NYU community;3) encourage Center investigators to explore new research initiatives;and 4) assist promising new investigators in establishing independent research in environmental health sciences. We have been very successful at achieving these four goals for the past ten years. The following are a few highlights of our successes in achieving these specific aims during the past five years. As one of the goals of this Center, efforts to understand the mechanisms of action, component composition, adverse health effects, mitigation and risks of ambient air exposures have been supported by a long and outstanding history in inhalation toxicology research. The PPP has worked diligently with Center faculty in achieving these goals. PPP funding has supported the establishment of a novel organ bath system that allowed for novel collaborative research conducted by Drs. L.-C. Chen and Lippmann in the assessment of the vascular function of aorta rings and small arteries. We have also provided PPP funding for the development of a new method of inhalation exposure: a

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES000260-48A1
Application #
8279597
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1997-04-01
Project End
2017-03-31
Budget Start
2012-04-27
Budget End
2013-03-31
Support Year
48
Fiscal Year
2012
Total Cost
$229,464
Indirect Cost
$86,049
Name
New York University
Department
Type
DUNS #
121911077
City
New York
State
NY
Country
United States
Zip Code
10016
Zhang, Xiaoru; Kluz, Thomas; Gesumaria, Lisa et al. (2016) Solar Simulated Ultraviolet Radiation Induces Global Histone Hypoacetylation in Human Keratinocytes. PLoS One 11:e0150175
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Zakhar, Joseph; Amrock, Stephen M; Weitzman, Michael (2016) Passive and Active Tobacco Exposure and Children's Lipid Profiles. Nicotine Tob Res 18:982-7
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McClintock, Tyler R; Parvez, Faruque; Wu, Fen et al. (2016) Major dietary patterns and carotid intima-media thickness in Bangladesh. Public Health Nutr 19:218-29
Howe, Caitlin G; Liu, Xinhua; Hall, Megan N et al. (2016) Sex-specific associations between one-carbon metabolism indices and posttranslational histone modifications in arsenic-exposed Bangladeshi adults. Cancer Epidemiol Biomarkers Prev :
Park, Sung-Hyun; Xie, Steve; Rao, Chinthalapally V et al. (2016) Haplo-insufficiency of both BubR1 and SGO1 accelerates cellular senescence. J Hematol Oncol 9:7

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