In accord with the goals and strategic vision of the Center, the Career Development Program (CDP) has three major goals. These include: 1) successful mentoring and career development of junior faculty; 2) recruitment and mentoring of investigators new to environmental health sciences research, and, 3) providing Center investigators with opportunities and access to resources and technologies that will advance research programs in accord with Center goals and vision. The mission of the University of Rochester Environmental Health Sciences Center (EHSC) is to identify the means by which environmental and chemical exposures act as modifying factors for human disease and dysfunction, and to use this information to prevent or ameliorate adverse health consequences and thereby improve public health. This mission is achieved by the integration of basic science with clinical research, and the translation of this research through community outreach, education, and prevention. This is also achieved by enhancing the career development of talented environmental health investigators. The areas of research emphasis for the EHSC are Pulmonary &Cardiovascular Diseases, Neurodevelopmental Disorders &Neurodegerierative Diseases, and Musculoskeletal Diseases. The Pulmonary &Cardiovascular Disease Program brings together a multidisciplinary group of scientists whose research focuses on the impact of several types of environmental exposures on cardiopulmonary health. These exposures include ambient and occupational particulates, oxidant gases, ionizing radiation, and engineered nanoparticles. The Neurodevelopmental Disorders &Neurodegenerative Disease Program is focused on the effects of early developmental exposures to neurotoxicants and the consequences to cognitive, motor, and sensory function. This group is also directed at later, emergent, neurodegenerative diseases induced by these agents. The Musculoskeletal Disease Program is dedicated to producing molecular and cellular advances related to the effects of toxicants on tissues comprising the bones and joints. These advances are translated into studies performed in animal models with the ultimate goal of moving the work into human studies and clinical trials. The efforts of these Programs are promoted and assisted through two Facility Cores: Biostatistics and the Integrative Health Sciences Facility. The latter consists of Translational Services, an Animal/Human Inhalation Facility, and an Animal/Human Behavioral Sciences Facility. Collaborations, career development, and new directions are significantly enhanced through a Pilot Project Program and Career Development Program. The Community Outreach &Education Core is a source of environmental health information for the entire community, and promotes interdisciplinary research, translation, prevention, and engagement activities. Oversight of all Center functions and programs occurs through the Administrative Core.
The broad goals of this Center are to establish innovative programs of excellence in environmental health sciences by providing scientific and programmatic support. This Center provides the framework to generate novel research findings and then convert these into critical information, resources, and tools that can be used by public health officials, medical professionals, and the community to prevent disease and improve public health.
|Reilly, Emma C; Martin, Kyle C; Jin, Guang-bi et al. (2015) Neonatal hyperoxia leads to persistent alterations in NK responses to influenza A virus infection. Am J Physiol Lung Cell Mol Physiol 308:L76-85|
|Rand, Matthew D (2014) A method of permeabilization of Drosophila embryos for assays of small molecule activity. J Vis Exp :|
|Gardner, Blake; Ling, Frederick; Hopke, Philip K et al. (2014) Ambient fine particulate air pollution triggers ST-elevation myocardial infarction, but not non-ST elevation myocardial infarction: a case-crossover study. Part Fibre Toxicol 11:1|
|Oller, Adriana R; Oberdörster, Günter; Seilkop, Steven K (2014) Derivation of PM10 size-selected human equivalent concentrations of inhaled nickel based on cancer and non-cancer effects on the respiratory tract. Inhal Toxicol 26:559-78|
|Montgomery, Sara L; Vorojeikina, Daria; Huang, Wen et al. (2014) Genome-wide association analysis of tolerance to methylmercury toxicity in Drosophila implicates myogenic and neuromuscular developmental pathways. PLoS One 9:e110375|
|Wheeler, Jennifer L H; Martin, Kyle C; Resseguie, Emily et al. (2014) Differential consequences of two distinct AhR ligands on innate and adaptive immune responses to influenza A virus. Toxicol Sci 137:324-34|
|Orlando, Mark S; Dziorny, Adam C; Harrington, Donald et al. (2014) Associations between prenatal and recent postnatal methylmercury exposure and auditory function at age 19 years in the Seychelles Child Development Study. Neurotoxicol Teratol 46:68-76|
|Sundar, Isaac K; Nevid, Michael Z; Friedman, Alan E et al. (2014) Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer. J Proteome Res 13:982-96|
|Prince, Lisa; Korbas, Malgorzata; Davidson, Philip et al. (2014) Target organ specific activity of drosophila MRP (ABCC1) moderates developmental toxicity of methylmercury. Toxicol Sci 140:425-35|
|Regal, Jean F; Lawrence, B Paige; Johnson, Alex C et al. (2014) Neonatal oxygen exposure alters airway hyper-responsiveness but not the response to allergen challenge in adult mice. Pediatr Allergy Immunol 25:180-6|
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