Abstract

A. STRATEGIC VISION AND IMPACT ON ENVIRONMENTAL HEALTH Over the past 35 years, the University of Rochester Environmental Health Sciences Center (EHSC) has achieved national and international distinction for its contributions to research and training in the environmental health sciences. Through a strong multi- and interdisciplinary framework, we have fostered advances in both basic and translational research examining the relationships between environmental exposures and human disease. The areas of research emphasis for the EHSC are Pulmonary &Cardiovascular Diseases, Neurodevelopment Disorders &Neurodegenerative Diseases, and Musculoskeletal Diseases.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES001247-39
Application #
8448224
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
39
Fiscal Year
2013
Total Cost
$147,463
Indirect Cost
$52,018

  Institution

Name
University of Rochester
Department
Type
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Sobolewski, Marissa; Conrad, Katherine; Marvin, Elena et al. (2018) Endocrine active metals, prenatal stress and enhanced neurobehavioral disruption. Horm Behav 101:36-49
Klocke, Carolyn; Allen, Joshua L; Sobolewski, Marissa et al. (2018) Exposure to fine and ultrafine particulate matter during gestation alters postnatal oligodendrocyte maturation, proliferation capacity, and myelination. Neurotoxicology 65:196-206
McSorley, Emeir M; Yeates, Alison J; Mulhern, Maria S et al. (2018) Associations of maternal immune response with MeHg exposure at 28 weeks' gestation in the Seychelles Child Development Study. Am J Reprod Immunol 80:e13046
Duffney, Parker F; Falsetta, Megan L; Rackow, Ashley R et al. (2018) Key roles for lipid mediators in the adaptive immune response. J Clin Invest 128:2724-2731
Morris-Schaffer, Keith; Sobolewski, Marissa; Allen, Joshua L et al. (2018) Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice. Neurotoxicology 67:234-244
Willis, Mary D; Jusko, Todd A; Halterman, Jill S et al. (2018) Unconventional natural gas development and pediatric asthma hospitalizations in Pennsylvania. Environ Res 166:402-408
Wahlberg, Karin; Love, Tanzy M; Pineda, Daniela et al. (2018) Maternal polymorphisms in glutathione-related genes are associated with maternal mercury concentrations and early child neurodevelopment in a population with a fish-rich diet. Environ Int 115:142-149
Cholette, Jill M; Pietropaoli, Anthony P; Henrichs, Kelly F et al. (2018) Elevated free hemoglobin and decreased haptoglobin levels are associated with adverse clinical outcomes, unfavorable physiologic measures, and altered inflammatory markers in pediatric cardiac surgery patients. Transfusion 58:1631-1639
Boule, Lisbeth A; Burke, Catherine G; Jin, Guang-Bi et al. (2018) Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather than chemical source is the stronger predictor of outcome. Sci Rep 8:1826
Lacy, Shannon H; Woeller, Collynn F; Thatcher, Thomas H et al. (2018) Activated Human Lung Fibroblasts Produce Extracellular Vesicles with Anti-Fibrotic Prostaglandins. Am J Respir Cell Mol Biol :

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