The primary mission of MIT's COEC program is to raise awareness and understanding of the impact of the environment on health. Awareness is the first step toward change, and therefore through educational outreach, we aim to empower citizens to prevent environmentally induced diseases by providing them with knowledge to help inform wise choices. While COEC activities reach people of all ages, it is the philosophy of this COEC to focus upon youth, a critical at-risk portion of our community who can benefit tremendously from knowledge that will help them make better life choices. Furthermore, understanding environmental health and understanding the fundamentals of life sciences go hand-in-hand, thus providing the dual benefit of informed decision-making, and inspiration in science. Therefore, MIT COEC proposes to continue with its emphasis on youth, while at the same time extending programmatic opportunities to teachers and health care professionals, who are best poised to disseminate valuable environmental health information to the community. This COEC group continues to be innovative both in terms of the conceptual materials covered, but also in terms of the pedagogical tools. Through the development of novel hands-on programs, hundreds of students have become Involved in the learning process, and thus receptive to important concepts about the environment and its impact on their health. In addition, this past cycle, COEC reached out not only to students, but also to thousands of community members of all ages, through a variety of media, including participatory workshops, museum exhibitions, training programs, laboratory experiments, and professional videos. In close alignment with the core interests of the Center, and under strong leadership to streamline the program and optimize its direction, COEC has successfully improved the public understanding of the impact of the environment on health, by connecting the impact of exposures to basic cellular processes.
The specific aims for this next funding period are thus focused on activities that will continue to teach fundamental concepts in environmental health to community members of all ages, with emphasis on to students, teachers, health care professionals.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Center Core Grants (P30)
Project #
Application #
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Massachusetts Institute of Technology
United States
Zip Code
Mannion, Anthony; Shen, Zeli; Feng, Yan et al. (2016) Draft Genome Sequences of Five Novel Polyketide Synthetase-Containing Mouse Escherichia coli Strains. Genome Announc 4:
Shabab, Mohammed; Arnold, Markus F F; Penterman, Jon et al. (2016) Disulfide cross-linking influences symbiotic activities of nodule peptide NCR247. Proc Natl Acad Sci U S A 113:10157-62
Milani, Pamela; Escalante-Chong, Renan; Shelley, Brandon C et al. (2016) Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells. Sci Rep 6:25474
Din, M Omar; Danino, Tal; Prindle, Arthur et al. (2016) Synchronized cycles of bacterial lysis for in vivo delivery. Nature 536:81-5
Yu, Amy Marie; Calvo, Jennifer A; Muthupalani, Suresh et al. (2016) The Mbd4 DNA glycosylase protects mice from inflammation-driven colon cancer and tissue injury. Oncotarget 7:28624-36
Manley, Leigh J; Ma, Duanduan; Levine, Stuart S (2016) Monitoring Error Rates In Illumina Sequencing. J Biomol Tech 27:125-128
Woods, Stephanie E; Ek, Courtney; Shen, Zeli et al. (2016) Male Syrian Hamsters Experimentally Infected with Helicobacter spp. of the H. bilis Cluster Develop MALT-Associated Gastrointestinal Lymphomas. Helicobacter 21:201-17
Spencer, Sarah J; Tamminen, Manu V; Preheim, Sarah P et al. (2016) Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers. ISME J 10:427-36
Mackos, A R; Galley, J D; Eubank, T D et al. (2016) Social stress-enhanced severity of Citrobacter rodentium-induced colitis is CCL2-dependent and attenuated by probiotic Lactobacillus reuteri. Mucosal Immunol 9:515-26
Zimanyi, Christina M; Chen, Percival Yang-Ting; Kang, Gyunghoon et al. (2016) Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife 5:e07141

Showing the most recent 10 out of 927 publications