10 PILOT GRANT PROGRAM 10.1 GOALS AND SUMMARY OF ACCOMPLISHMENTS The Pilot Grant Program has been a highly valued component of the EHSRC, serving the research, career development and training missions of the Center. The Pilot Grant Program has helped advance the careers of talented junior investigators by bringing them into environmental health science (EHS) research. It has fostered innovation and nurtured novel ideas fueling further grant support and publication (Please see Appendix B). The EHSRC will devote $218,000 per year to the pilot grant program from Center funds. However at the initiative of the EHSRC, additional funds, $60,000 - $90,000 per year, will be available from the Office of the Vice President for Research (through the Biological Sciences Program) to support EHS pilot grants. Also this year a new initiative was begun with the Institute for Clinical and Translational Science (ICTS) Pilot Grant Program to support one $50,000 EHS-related pilot grant. The Biological Sciences Program and the ICTS Pilot Grant Program are independently administered, providing at least three independent mechanisms for funding research initiatives, especially for junior scientists, in the field of EHS. The Goals of the EHSRC Pilot Grant Program are to: ? Provide initial support for junior investigators to establish new lines of environmental health research ? Provide services of state-of-the-art facilities to pilot grant investigators to enhance their research and reduce their costs ? Facilitate exploration of innovative new directions in environmental health for established investigators ? Stimulate investigators from other disciplines to apply their expertise to environmental health research ? Foster new interdisciplinary collaborations through awarding of pilot projects to investigators who have not previously worked together The objective measures of the success of the program are: ? Grants and contracts developed as progeny of pilot grants ? Manuscripts emanating from the pilot grant support ? Students mentored and M.S. theses and Ph.D. dissertations generated through pilot grant support ? Post-doctoral fellows mentored in research and grantsmanship through the Pilot Grant Program ? New interdisciplinary collaborations established as a result of the program ? Career development and advancement for faculty in EHS The pilot grant program has been extremely successful in meeting these objectives. As shown in Table 10.1, the EHSRC has funded 122 pilot grants since it was inaugurated in 1990 (Please see Appendix B). These have been in two categories, the Research Pilots where research was carried out in the U.S. and International Pilots, where the focus was studies abroad. There have been 106 projects funded through the Research Pilot Grant Program and 16 through the International Pilot Grant Program. Table 10.1 provides data demonstrating the success rate for pilot grant submissions, a 58% success rate for Research Pilot Grant applications and 55% for International Pilot applications. In the current grant cycle (2007 - present), 24 pilot grants were funded, of which only one was an International Pilot Grant (Table E.I). Nearly all funded pilot grants were projects involving junior investigators and the majority of awards having been awarded to junior principal investigators. Since 2003 there has been only one International Pilot Grant funded. This low application/funding rate reflects a shift in the focus of our NIH-funded Center for International Rural and Environmental Health. Therefore in the next funding cycle, we will fold the International pilots into the regular funding mechanism and discontinue this grant category. Since the founding of the EHSRC, investments in the Pilot Grant Programs ($2,157,417) have produced grant progeny with a value of $47,939,311, a more than 22-fold return on investment (please see Appendix B). This success has no doubt been at least partially responsible for the newer partnerships with the Biological Sciences Program and the ICTS program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
2P30ES005605-22
Application #
8279705
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
2012-05-01
Project End
2017-03-31
Budget Start
2012-05-01
Budget End
2013-03-31
Support Year
22
Fiscal Year
2012
Total Cost
$300,101
Indirect Cost
$111,180
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Gottipati, Koteswara R; Bandari, Shiva Kumar; Nonnenmann, Matthew W et al. (2015) Transcriptional mechanisms and protein kinase signaling mediate organic dust induction of IL-8 expression in lung epithelial and THP-1 cells. Am J Physiol Lung Cell Mol Physiol 308:L11-21
Heard, Jason P; McDonald, Kara M; Xing, Yunfan et al. (2015) Regional and national review of factors associated with burn wound cellulitis. J Burn Care Res 36:23-32
Chang, Eugene H; Tang, Xiao Xiao; Shah, Viral S et al. (2015) Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor. Int Forum Allergy Rhinol 5:178-81
Barros, Nirmalla; Field, Dan W; Steck, Daniel J et al. (2015) Comparative survey of outdoor, residential and workplace radon concentrations. Radiat Prot Dosimetry 163:325-32
Rigler, Shannon L; Kay, Denise M; Sicko, Robert J et al. (2015) Novel copy-number variants in a population-based investigation of classic heterotaxy. Genet Med 17:348-57
Zhu, Yong; Romitti, Paul A; Caspers Conway, Kristin M et al. (2015) Genitourinary health in a population-based cohort of males with Duchenne and Becker Muscular dystrophies. Muscle Nerve 52:22-7
Berton, G; Castaldi, M A; Cassatella, M A et al. (2015) Editorial: Celebrating the 50th anniversary of the seminal discovery that the phagocyte respiratory burst enzyme is an NADPH oxidase. J Leukoc Biol 97:2-Jan
Kilburg-Basnyat, Brita; Metwali, Nervana; Thorne, Peter S (2015) Effect of deployment time on endotoxin and allergen exposure assessment using electrostatic dust collectors. Ann Occup Hyg 59:104-15
Wu, Xianai; Barnhart, Christopher; Lein, Pamela J et al. (2015) Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice. Environ Sci Technol 49:616-25
Cyr, A R; Kulak, M V; Park, J M et al. (2015) TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis. Oncogene 34:436-44

Showing the most recent 10 out of 429 publications