Overall Objective and Specific Aims: Tomorrow's generation of beginning researchers will need comprehensive approaches for integrating environmental health sciences (EHS) with basic, clinical, computational biology, and public health research. These investigators will engage in multidisciplinary research where they will need to translate how model systems can be used in the study of disease in humans. It has been our experience that junior faculty and those still in training usually have minimal research skills, often feel daunted by the research process and have no-to-minimal understanding about the role of EHS. Thus, it is imperative for these future investigators to develop their skills for forging new partnerships and integrating the role of environmental exposures in new health and disease paradigms. The goal is to increase their awareness of the revolutionary technologies of biomedical sciences, many available in the Center for Environmental Genetics (CEG), and how these can be translated from the basic lab science to human studies and ultimately practices and personalized medicine. Mentorship and career development brings fresh ideas and enthusiasm to the CEG as well, so the relationship becomes reciprocal. Thus, it is a priority of the CEG and the CDP to identify and develop the careers of promising early stage investigators. To accomplish this goal, the overall objective ofthe career development program (CDP) s to recruit, enrich, encourage and provide resources and mentoring activities to investigators at the graduate, postgraduate and early faculty levels with a particular emphasis on EHS. The CDP has forged new cross-disciplinary partnerships in areas applicable to EHS with basic, epidemiological, and/or clinical studies including studies in molecular genetics and epigenetics, molecular biology, clinical and environmental epidemiology and environmental toxicology.

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Center Core Grants (P30)
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Environmental Health Sciences Review Committee (EHS)
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University of Cincinnati
United States
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Zhang, Hongmei; Yolton, Kimberly; Webster, Glenys M et al. (2018) Prenatal and childhood perfluoroalkyl substances exposures and children's reading skills at ages 5 and 8years. Environ Int 111:224-231
Sharma, Manju; Zhang, Xiang; Huang, Shouxiong (2018) Integrate Imaging Flow Cytometry and Transcriptomic Profiling to Evaluate Altered Endocytic CD1d Trafficking. J Vis Exp :
Vuong, Ann M; Braun, Joseph M; Webster, Glenys M et al. (2018) Polybrominated diphenyl ether (PBDE) exposures and thyroid hormones in children at age 3?years. Environ Int 117:339-347
Pugh, Amanda M; Giannini, Courtney M; Pinney, Susan M et al. (2018) Characteristics and diagnosis of pregnancy and lactation associated breast cancer: Analysis of a self-reported regional registry. Am J Surg 216:809-812
Brunst, Kelly J; Tignor, Nicole; Just, Allan et al. (2018) Cumulative lifetime maternal stress and epigenome-wide placental DNA methylation in the PRISM cohort. Epigenetics 13:665-681
Alexander, Jacqueline; Teague, April M; Chen, Jing et al. (2018) Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy. PLoS One 13:e0190698
Kim, Dasom; Chen, Zi; Zhou, Lin-Fu et al. (2018) Air pollutants and early origins of respiratory diseases. Chronic Dis Transl Med 4:75-94
Brunst, Kelly J; Sanchez-Guerra, Marco; Chiu, Yueh-Hsiu Mathilda et al. (2018) Prenatal particulate matter exposure and mitochondrial dysfunction at the maternal-fetal interface: Effect modification by maternal lifetime trauma and child sex. Environ Int 112:49-58
Isiugo, Kelechi; Newman, Nicholas; Jandarov, Roman et al. (2018) Assessing the accuracy of commercially available gas sensors for the measurement of ambient ozone and nitrogen dioxide. J Occup Environ Hyg 15:782-791
Li, Tao; Hu, Rong; Chen, Zi et al. (2018) Fine particulate matter (PM2.5): The culprit for chronic lung diseasesĀ in China. Chronic Dis Transl Med 4:176-186

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