Abstract

The Integrative Health Sciences Facility Core (IHSFC) will enhance translation of research findings of studies of environmental factors in disease causation. The overall objectives will be accomplished through 1) expert consultation services in medicine, epidemiology, statistics, exposure assessment, 2) cohorts with environmental exposure data and biorepositories, 3) informatics tools and Forth and Back clinical research conferences, seminars and workshops that will mesh information from various disciplines for translation to the bedside and public health. Through providing these services and access to technologies, this IHSFC will build capacity for research that integrates basic science with clinical research and public health. The goal of the Core is to accelerate the transfer of basic biomedical knowledge from the laboratory to clinical applications in prevention, early detection, new treatments and, ultimately, to prolong and enhance life. The IHSFC will capitalize on the potential for synergy with other CEG components such as the Community Outreach and Engagement Core (COEC), Career Development Program (CDP), the Integrated Technologies Support Core (ITSC), Bioinformatics Core and the Pilot Projects Program (PPP).

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES006096-22
Application #
8670747
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
22
Fiscal Year
2014
Total Cost
$186,081
Indirect Cost
$68,680

  Institution

Name
University of Cincinnati
Department
Type
DUNS #
041064767
City
Cincinnati
State
OH
Country
United States
Zip Code
45221

  Publications

Bermúdez, Mei-Ling; Skelton, Matthew R; Genter, Mary Beth (2018) Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson's disease. Mol Genet Metab 125:305-313
Reigle, Beverly S; Zhang, Bin (2018) Women's Rehabilitation Experiences Following Breast Cancer Surgery. Rehabil Nurs 43:195-200
Whitt, Jordan; Woo, Vivienne; Lee, Patrick et al. (2018) Disruption of Epithelial HDAC3 in Intestine Prevents Diet-Induced Obesity in Mice. Gastroenterology 155:501-513
Uno, Shigeyuki; Nebert, Daniel W; Makishima, Makoto (2018) Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice. Food Chem Toxicol 113:73-82
Vuong, Ann M; Yolton, Kimberly; Poston, Kendra L et al. (2018) Childhood polybrominated diphenyl ether (PBDE) exposure and executive function in children in the HOME Study. Int J Hyg Environ Health 221:87-94
Lee, Alison G; Le Grand, Blake; Hsu, Hsiao-Hsien Leon et al. (2018) Prenatal fine particulate exposure associated with reduced childhood lung function and nasal epithelia GSTP1 hypermethylation: Sex-specific effects. Respir Res 19:76
Leung, Yuet-Kin; Ouyang, Bin; Niu, Liang et al. (2018) Identification of sex-specific DNA methylation changes driven by specific chemicals in cord blood in a Faroese birth cohort. Epigenetics 13:290-300
Kim, Stephani; Xu, Xijin; Zhang, Yuling et al. (2018) Metal concentrations in pregnant women and neonates from informal electronic waste recycling. J Expo Sci Environ Epidemiol :
Chen, Jing; Gálvez-Peralta, Marina; Zhang, Xiang et al. (2018) In utero gene expression in the Slc39a8(neo/neo) knockdown mouse. Sci Rep 8:10703
Abdel-Hameed, Enass A; Rouster, Susan D; Boyce, Ceejay L et al. (2018) Ultra-Deep Genomic Sequencing of HCV NS5A Resistance-Associated Substitutions in HCV/HIV Coinfected Patients. Dig Dis Sci 63:645-652

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