A. Objectives and Structure of the SWEHSC Administrative Core: (i) Objectives: The SWEHSC Administrative Core promotes research excellence in the environmental health sciences by facilitating SWEHSC initiatives on the University of Arizona Health Sciences Center (AHSC) campus, statewide, nationally, and internationally. The Administrative Core (i) provides the administrative framework within which the intellectual and technological expertise of its members is enhanced, (ii) provides leadership in creating an environment conducive to the development of interdisciplinary research, and (iii) assists its members in identifying translational research opportunities.
The Specific Aims of the Administrative Core are: 1. Foster and lead the development of new research initiatives within the SWEHSC, across the AHSC campus, state-wide, nationally (e.g. inter-NIEHS Center collaborations), and internationally (e.g. US/Mexico Border environmental health issues). 2. Coordinate and integrate the Research Focus Groups (RFGs) and Facility Cores (FCs) in all the activities of the SWEHSC. 3. Utilize the Pilot Project and other enrichment activities to recruit and nurture the emergence and development of new research themes and programs within the SWEHSC. 4. Use the Pilot Project Program and Career Development Core to nurture junior faculty and assisting them to incorporate environmental health sciences projects into their research efforts. 5. Use the Community Outreach Education Core to assist in the education and protection of at-risk populations in the arid Southwest. In addition, the Administrative Core is charged with the responsibility of overseeing the day-to-day operations of the SWEHSC and providing financial management for the Center. (ii) Overall Structure and Composition of the Administrative Core: The Administrative Core provides SWEHSC with the requisite organizational structure to pursue its mission and goals (see Figure 1 in

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Center Core Grants (P30)
Project #
Application #
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Arizona
United States
Zip Code
Dodson, Matthew; Liu, Pengfei; Jiang, Tao et al. (2018) Increased O-GlcNAcylation of SNAP29 drives arsenic-induced autophagic dysfunction. Mol Cell Biol :
Griggs, Chanel A; Malm, Scott W; Jaime-Frias, Rosa et al. (2018) Valproic acid disrupts the oscillatory expression of core circadian rhythm transcription factors. Toxicol Appl Pharmacol 339:110-120
Toth, Erica L; Li, Hui; Dzierlenga, Anika L et al. (2018) Gene-by-Environment Interaction of Bcrp-/- and Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition. Drug Metab Dispos 46:1478-1486
Malm, S W; Amouzougan, E A; Klimecki, W T (2018) Fetal bovine serum induces sustained, but reversible, epithelial-mesenchymal transition in the BEAS-2B cell line. Toxicol In Vitro 50:383-390
Rojo de la Vega, Montserrat; Zhang, Donna D; Wondrak, Georg T (2018) Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin. Front Pharmacol 9:287
Harris, Alondra P; Ismail, Kareem A; Nunez, Martha et al. (2018) Trichloroethylene perturbs HNF4a expression and activity in the developing chick heart. Toxicol Lett 285:113-120
Dzierlenga, Anika L; Cherrington, Nathan J (2018) Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis. J Biochem Mol Toxicol 32:e22035
Yellowhair, Monica; Romanotto, Michelle R; Stearns, Diane M et al. (2018) Uranyl acetate induced DNA single strand breaks and AP sites in Chinese hamster ovary cells. Toxicol Appl Pharmacol 349:29-38
Wales, Jessica A; Chen, Cheng-Yu; Breci, Linda et al. (2018) Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase. J Biol Chem 293:1850-1864
Lee, Sang C; Zhang, Jack; Strom, Josh et al. (2017) G-Quadruplex in the NRF2 mRNA 5' Untranslated Region Regulates De Novo NRF2 Protein Translation under Oxidative Stress. Mol Cell Biol 37:

Showing the most recent 10 out of 942 publications