I. MISSION AND OVERVIEW A. The Mission of the Southwest Environmental Health Science Center (SWEHSC) COEC is to promote awareness, appreciation, and comprehension of environmental health issues associated with the goals and vision of the SWEHSC. COEC uses the expertise of the SWEHSC investigators to provide services to concerned professional and public stakeholders. In addition, COEC provides a channel for gathering information related to stakeholders concerns and responding to community requests for information. The goals changed over the last funding period in response to the change in the NIEHS P30 Core Centers RFA requirements for outreach cores. The goals for the current funding period are addressed in the Established Community Outreach And Education section. The goals for the coming funding period are addressed in the Future Directions section. B. Overview and Rationale: The COEC will continue to serve as a bi-directional resource of information and expertise for surrounding communities, stakeholders and the Center. The COEC strives to further scientific collaborations and to disseminate research results. The initiatives the COEC fosters are a direct reflection of the COEC's assessment of the Environmental Health (EH) Science information needs of the target audiences and of requests from partners. The COEC provides assistance to partners with their outreach activities and education endeavors for adults and children focused around the environmental health (EH) topics of the SWEHSC;arsenic contamination, UV exposure, asthma, toxicology, oxidative stress, EH research methods, trichloroethylene exposure and environmental impacts on diabetes. A community centric philosophy (Watkins, 2009) drives COEC activities, relationships and interactions among SWEHSC and Target Audiences of Tribal communities, residents in Superfund areas, and educational communities in southern Arizona. Community is at the heart of COEC Figure 1. The COEC conducts most of its initiatives in partnership with Tribal, Community, and University associates, depicted in the next ring of the diagram. The COEC supports the SWEHSC mission of community involvement by translating and disseminating the research findings of SWEHSC scientists. By interacting with the Integrated Health Science Facility Core (IHS) the COEC assesses the EH information needs of communities, provides education about working with communities to scientists and their students, and educates community members about EH research in collaboration with SWEHSC scientists. The COEC supports NIEHS annual meetings with sessions about interacting with Tribal communities and collaborates with the outreach cores of other centers to develop materials and methods for outreach activities and evaluation, the outside ring of the diagram.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES006694-17
Application #
8464117
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2013-04-01
Budget End
2014-03-31
Support Year
17
Fiscal Year
2013
Total Cost
$142,887
Indirect Cost
$63,315
Name
University of Arizona
Department
Type
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721
Dodson, Matthew; Liu, Pengfei; Jiang, Tao et al. (2018) Increased O-GlcNAcylation of SNAP29 drives arsenic-induced autophagic dysfunction. Mol Cell Biol :
Griggs, Chanel A; Malm, Scott W; Jaime-Frias, Rosa et al. (2018) Valproic acid disrupts the oscillatory expression of core circadian rhythm transcription factors. Toxicol Appl Pharmacol 339:110-120
Toth, Erica L; Li, Hui; Dzierlenga, Anika L et al. (2018) Gene-by-Environment Interaction of Bcrp-/- and Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Steatohepatitis Alters SN-38 Disposition. Drug Metab Dispos 46:1478-1486
Malm, S W; Amouzougan, E A; Klimecki, W T (2018) Fetal bovine serum induces sustained, but reversible, epithelial-mesenchymal transition in the BEAS-2B cell line. Toxicol In Vitro 50:383-390
Rojo de la Vega, Montserrat; Zhang, Donna D; Wondrak, Georg T (2018) Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin. Front Pharmacol 9:287
Harris, Alondra P; Ismail, Kareem A; Nunez, Martha et al. (2018) Trichloroethylene perturbs HNF4a expression and activity in the developing chick heart. Toxicol Lett 285:113-120
Dzierlenga, Anika L; Cherrington, Nathan J (2018) Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis. J Biochem Mol Toxicol 32:e22035
Yellowhair, Monica; Romanotto, Michelle R; Stearns, Diane M et al. (2018) Uranyl acetate induced DNA single strand breaks and AP sites in Chinese hamster ovary cells. Toxicol Appl Pharmacol 349:29-38
Wales, Jessica A; Chen, Cheng-Yu; Breci, Linda et al. (2018) Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase. J Biol Chem 293:1850-1864
Lee, Sang C; Zhang, Jack; Strom, Josh et al. (2017) G-Quadruplex in the NRF2 mRNA 5' Untranslated Region Regulates De Novo NRF2 Protein Translation under Oxidative Stress. Mol Cell Biol 37:

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