MISSION AND GOALS OF THE FUNCTIONAL GENOMICS &PROTEOMICS FACILITY CORE (FGP-FC) The FGP-FC plays a crucial role in supporting the Center's mission to identify the interactions between genetic, epigenetic and environmental factors that contribute to major chronic diseases. The FGP-FC does this by providing state-of-the-art genomics and proteomics technologies to investigate gene-environment interactions in the context of environmental health sciences research and population-based studies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES007033-19
Application #
8650854
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
19
Fiscal Year
2014
Total Cost
$358,660
Indirect Cost
$128,750
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Schaupp, Christopher M; White, Collin C; Merrill, Gary F et al. (2015) Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3. Chem Biol Interact 234:154-61
Wegner, Susanna H; Yu, Xiaozhong; Pacheco Shubin, Sara et al. (2015) Stage-specific signaling pathways during murine testis development and spermatogenesis: A pathway-based analysis to quantify developmental dynamics. Reprod Toxicol 51:31-9
Cole, Toby B; Li, Wan-Fen; Co, Aila L et al. (2014) Repeated gestational exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1) modulated effects in maternal and fetal tissues. Toxicol Sci 141:409-22
Hiolski, Emma M; Kendrick, Preston S; Frame, Elizabeth R et al. (2014) Chronic low-level domoic acid exposure alters gene transcription and impairs mitochondrial function in the CNS. Aquat Toxicol 155:151-9
Penning, Trevor M; Breysse, Patrick N; Gray, Kathleen et al. (2014) Environmental health research recommendations from the Inter-Environmental Health Sciences Core Center Working Group on unconventional natural gas drilling operations. Environ Health Perspect 122:1155-9
Woods, James S; Heyer, Nicholas J; Russo, Joan E et al. (2014) Genetic polymorphisms affecting susceptibility to mercury neurotoxicity in children: summary findings from the Casa Pia Children's Amalgam clinical trial. Neurotoxicology 44:288-302
Pizzurro, Daniella M; Dao, Khoi; Costa, Lucio G (2014) Diazinon and diazoxon impair the ability of astrocytes to foster neurite outgrowth in primary hippocampal neurons. Toxicol Appl Pharmacol 274:372-82
Roth, J A; Boudreau, D; Fujii, M M et al. (2014) Genetic risk factors for major bleeding in patients treated with warfarin in a community setting. Clin Pharmacol Ther 95:636-43
Kemp, Christopher J; Moore, James M; Moser, Russell et al. (2014) CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer. Cell Rep 7:1020-9
Woods, James S; Heyer, Nicholas J; Russo, Joan E et al. (2014) Genetic polymorphisms of catechol-O-methyltransferase modify the neurobehavioral effects of mercury in children. J Toxicol Environ Health A 77:293-312

Showing the most recent 10 out of 519 publications