/Aims The overall goal of the IHSFC is to facilitate both patient-oriented and population-based research within the Center for Environmental Health in Northern Manhattan (CEHNM). It promotes the strategic goals of the CEHNM by supporting existing research projects and fostering new interdisciplinary activities focusing on environmental health problems. The Core provides the infrastructure to carry out these studies and has several components including epidemiologic, data management and biostatistical capabilities and a Biomarkers Laboratory for sample processing, distribution and analysis. The Core addresses the needs of CEHNM investigators as their research focus changes and develops and validates new methods and assays to meet these changing needs. The Core provides extremely efficient, cost-effective cutting-edge web-based and other database management systems, which have expanded to include a major formal educational component. The CEHNM made a strategic decision early on to dedicate significant resources to data management because investigators often lacked expertise in this area. The Center provides data management consulting, programming and an extensive, secure, hardware/network infrastructure. Ms. Levy also developed a data management course that addresses all aspects of data management open to all members of the CEHNM. We took the concept a step further and now offer workshops to Center members who cannot devote a full semester to the course being offered. The IHSFC offers pro-bono or low-cost services for CEHNM pilot projects. Training is an important component of Core activities, allowing methodologies to be exported to other laboratories, providing access to equipment and the expertise necessary to conduct studies requiring immunoassays for DNA adducts, oxidative stress markers and other parameters, genotyping and DNA methylation and most recently, microRNA analysis. It educates students and post docs on the importance of sample batching, quality control and assay reliability.

Agency
National Institute of Health (NIH)
Type
Center Core Grants (P30)
Project #
5P30ES009089-16
Application #
8664381
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
Budget End
Support Year
16
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
Jung, Kyung Hwa; Perzanowski, Matthew; Rundle, Andrew et al. (2014) Polycyclic aromatic hydrocarbon exposure, obesity and childhood asthma in an urban cohort. Environ Res 128:35-41
Yan, Beizhan; Bopp, Richard F; Abrajano, Teofilo A et al. (2014) Source apportionment of polycyclic aromatic hydrocarbons (PAHs) into Central Park Lake, New York City, over a century of deposition. Environ Toxicol Chem 33:985-92
Petkova, Elisaveta P; Bader, Daniel A; Anderson, G Brooke et al. (2014) Heat-related mortality in a warming climate: projections for 12 U.S. cities. Int J Environ Res Public Health 11:11371-83
Yang, Wan; Karspeck, Alicia; Shaman, Jeffrey (2014) Comparison of filtering methods for the modeling and retrospective forecasting of influenza epidemics. PLoS Comput Biol 10:e1003583
McAllister, David A; Ahmed, Firas S; Austin, John H M et al. (2014) Emphysema predicts hospitalisation and incident airflow obstruction among older smokers: a prospective cohort study. PLoS One 9:e93221
Chretien, Jean-Paul; George, Dylan; Shaman, Jeffrey et al. (2014) Influenza forecasting in human populations: a scoping review. PLoS One 9:e94130
Ramírez-Ortiz, Marco A; Ponce-Castañeda, M Veronica; Cabrera-Muñoz, M Lourdes et al. (2014) Diagnostic delay and sociodemographic predictors of stage at diagnosis and mortality in unilateral and bilateral retinoblastoma. Cancer Epidemiol Biomarkers Prev 23:784-92
Herbstman, Julie B; Mall, Jennifer K (2014) Developmental Exposure to Polybrominated Diphenyl Ethers and Neurodevelopment. Curr Environ Health Rep 1:101-112
McCullough, Lauren E; Santella, Regina M; Cleveland, Rebecca J et al. (2014) Polymorphisms in DNA repair genes, recreational physical activity and breast cancer risk. Int J Cancer 134:654-63
Louis, Elan D; Lee, Michelle; Cortés, Etty et al. (2014) Matching asymmetry of tremor with asymmetry of postmortem cerebellar hemispheric changes in essential tremor. Cerebellum 13:462-70

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