The primary mission of the Integrative Health Sciences Facility Core (IHSFC) is to support CEHS investigators who conduct research using human study participants. IHSFC addresses four broad areas of interest. First, the IHSFC provides scientific consultation for clinical and population-based studies. These services promote collaborations and enhance scientific productivity. Second, biospecimen processing and genotyping sub-core laboratories provide platforms for short-term pilot projects and long-term epidemiologic studies for Center members. These sub-core laboratories provide access to state of the art equipment and a high level of quality control and maximal throughput that could not be achieved by individual investigators. The genotyping sub-core also provides typing of laboratory rodent strains in order to promote cross-disciplinary collaborations in functional and comparative genomics for Center members. Third, the IHSFC provides expertise in spatial analysis and geographic information systems, in order to integrate human epidemiologic studies with environmental exposure measurement. Fourth, the IHSFC serves as a liaison to a variety of core laboratories, resources and facilities at UNC that are of use to specific CEHS investigators. The IHSFC is closely integrated with the Biostatistics and Bioinformatics Facility Core (BBFC) and the Systems Biology Facility Core (SBFC) through the Research Navigator and the Flexible Interdisciplinary Research Groups (FIRG).

National Institute of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Center Core Grants (P30)
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Environmental Health Sciences Review Committee (EHS)
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University of North Carolina Chapel Hill
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Rummo, Pasquale E; Albrecht, Sandra S; Gordon-Larsen, Penny (2015) Field validation of food outlet databases: the Latino food environment in North Carolina, USA. Public Health Nutr 18:977-82
Edwards, Sharon E; Maxson, Pamela; Miranda, Marie Lynn et al. (2015) Cadmium levels in a North Carolina cohort: Identifying risk factors for elevated levels during pregnancy. J Expo Sci Environ Epidemiol 25:427-32
Angelon-Gaetz, K A; Richardson, D B; Lipton, D M et al. (2015) The effects of building-related factors on classroom relative humidity among North Carolina schools participating in the 'Free to Breathe, Free to Teach' study. Indoor Air 25:620-30
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Smith, Genee S; Schoenbach, Victor J; Richardson, David B et al. (2014) Particulate air pollution and susceptibility to the development of pulmonary tuberculosis disease in North Carolina: an ecological study. Int J Environ Health Res 24:103-12
Wen, Wanqing; Zheng, Wei; Okada, Yukinori et al. (2014) Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. Hum Mol Genet 23:5492-504
Fry, Rebecca C; Rager, Julia E; Bauer, Rebecca et al. (2014) Air toxics and epigenetic effects: ozone altered microRNAs in the sputum of human subjects. Am J Physiol Lung Cell Mol Physiol 306:L1129-37
Bradshaw, Patrick T; Ibrahim, Joseph G; Khankari, Nikhil et al. (2014) Post-diagnosis physical activity and survival after breast cancer diagnosis: the Long Island Breast Cancer Study. Breast Cancer Res Treat 145:735-42
Stingone, Jeanette A; Luben, Thomas J; Daniels, Julie L et al. (2014) Maternal exposure to criteria air pollutants and congenital heart defects in offspring: results from the national birth defects prevention study. Environ Health Perspect 122:863-72
Harmon, Quaker E; Engel, Stephanie M; Wu, Michael C et al. (2014) Polymorphisms in inflammatory genes are associated with term small for gestational age and preeclampsia. Am J Reprod Immunol 71:472-84

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