The Pilot Project Program is a key component of the Center of Excellence in Environmental Toxicology (CEET), The Pilot Project Program is aimed at funding new directions in environmental health research. These grants represent one vehicle by which the Center can continue to enrich, attract and support innovative research that may not be ready for direct NIH-funding, In addition, Pilot Projects can be used to fund collaborative research that may become a component of a multi-investigator award, the development of technologies that may benefit other CEET investigators, and to take the CEET into new directions. The Pilot Project Program serves to attract junior investigators and established faculty new to environmental health sciences to the CEET. The Program encourages applications that address community-based needs and can be proposed by COEC members. The Pilot Project Program also encourages applications that will seed patient and human population-based research that may require the resources of the Integrative Health Sciences Facility Core (IHSFC). This Program represents an important vehicle by which the Center can rejuvenate its membership and draw natural alliances with new faculty. The goals of the Pilot Project Program are to: ? Support career development of junior faculty in environmental health science ? Attract established investigators into environmental health science ? Develop technologies that may benefit other CEET investigators ? Fund collaborative research that may lead to multi-investigator grant applications ? Stimulate translational research themes in environmental health science ? Fund community based research projects identified by COEC members ? Fund patient and population based exposure research that will utilize the IHSFC The CEET is in its third year of funding and has awarded 14 Pilot Projects. Four of these awards were funded January 01, 2009. Of the ten Pilot Projects that have had sufficient time to provide a return on the investment, $4,085,050 in direct costs have been generated for an investment of $225,000 which is greater than 18:1. This value is deflated to 13.1: 1 if the newly funded Pilot Projects are counted. Pilot Project funding has led to 12 articles published in the scientific literature.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Center Core Grants (P30)
Project #
5P30ES013508-09
Application #
8650878
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
9
Fiscal Year
2014
Total Cost
$217,884
Indirect Cost
$79,421
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Furman, Ran; Lee, Jin V; Axelsen, Paul H (2018) Analysis of eicosanoid oxidation products in Alzheimer brain by LC-MS with uniformly 13C-labeled internal standards. Free Radic Biol Med 118:108-118
Zacharias, William J; Frank, David B; Zepp, Jarod A et al. (2018) Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. Nature 555:251-255
Piette, Elizabeth R; Moore, Jason H (2018) Improving machine learning reproducibility in genetic association studies with proportional instance cross validation (PICV). BioData Min 11:6
Fisher, Aron B; Vasquez-Medina, Jose P; Dodia, Chandra et al. (2018) Peroxiredoxin 6 phospholipid hydroperoxidase activity in the repair of peroxidized cell membranes. Redox Biol 14:41-46
Beaulieu-Jones, Brett K; Lavage, Daniel R; Snyder, John W et al. (2018) Characterizing and Managing Missing Structured Data in Electronic Health Records: Data Analysis. JMIR Med Inform 6:e11
Boland, Mary Regina; Kraus, Marc S; Dziuk, Eddie et al. (2018) Cardiovascular Disease Risk Varies by Birth Month in Canines. Sci Rep 8:7130
Beaumont, Robin N; Warrington, Nicole M; Cavadino, Alana et al. (2018) Genome-wide association study of offspring birth weight in 86?577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Hum Mol Genet 27:742-756
Cui, Naixue; Deatrick, Janet A; Liu, Jianghong (2018) Maternal and paternal physical abuse: Unique and joint associations with child behavioral problems. Child Abuse Negl 76:524-532
Romero, Freddy; Hong, Xu; Shah, Dilip et al. (2018) Lipid Synthesis Is Required to Resolve Endoplasmic Reticulum Stress and Limit Fibrotic Responses in the Lung. Am J Respir Cell Mol Biol 59:225-236
Barrett, Emily S; Vitek, Wendy; Mbowe, Omar et al. (2018) Allostatic load, a measure of chronic physiological stress, is associated with pregnancy outcomes, but not fertility, among women with unexplained infertility. Hum Reprod 33:1757-1766

Showing the most recent 10 out of 835 publications