The Instrument Shop Module is housed in a newly renovated 800 square-foot facility on the first floor of the Kellogg Eye Center. This space was acquired by this Module during this granting period and illustrates the commitment of the Department of Ophthalmology and Vision Sciences to supporting the facilities of the Core Center. Prior to 2005, this Module had only 320 square feet of space dispersed in several rooms adjacent to the Vivarium on the 8th floor of the research tower. The significant augmentation of space has resulted in greater efficiency and, as a result, the productivity of this Module has increased by approximately 40%. Previously, each time a large piece of equipment was required for a project, it had to be laboriously moved from a storage room into the workroom. Now the instrument maker can rapidly move from machine to machine and can also have multiple machines in use simultaneously. The Instrument Shop will not be moving into the new building in 2010. Equipment in this Module includes a rebuilt Harding lathe (model HLV) with Mitsuyo readouts; a Bridgeport milling machine (model J280843) with a 42"""""""" standard table and a 12"""""""" Yuasa rotary table, servopower, and infinitely variable speed; a metal vertical band saw; a Tennsmith squaring shear; a Tennsmith hand brake; and for instrument design purposes, a personal computer, CAD software, and a LaserJet printer. Staffing the Instrument Shop is Scott Szalay, a full-time Instrument Maker II, who has held this position for the past 13 years. He is very proficient at working with participating investigators to design a variety of noncommercially available devices that are necessary for NEI-supported research projects. Mr. Szalay's many years of practical experience allow him to expertly fabricate a wide range of devices.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY007003-22
Application #
7616698
Study Section
Special Emphasis Panel (ZEY1)
Project Start
Project End
Budget Start
2008-05-01
Budget End
2009-04-30
Support Year
22
Fiscal Year
2008
Total Cost
$152,690
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Eason, Jessica; Williams, Antionette L; Chawla, Bahaar et al. (2017) Differences in neural crest sensitivity to ethanol account for the infrequency of anterior segment defects in the eye compared with craniofacial anomalies in a zebrafish model of fetal alcohol syndrome. Birth Defects Res 109:1212-1227
Smith, Terry J; Kahaly, George J; Ezra, Daniel G et al. (2017) Teprotumumab for Thyroid-Associated Ophthalmopathy. N Engl J Med 376:1748-1761
Pawar, Mercy; Busov, Boris; Chandrasekhar, Aaruran et al. (2017) FAS apoptotic inhibitory molecule 2 is a stress-induced intrinsic neuroprotective factor in the retina. Cell Death Differ 24:1799-1810
Shahi, Pawan K; Liu, Xinling; Aul, Bryce et al. (2017) Abnormal Electroretinogram after Kir7.1 Channel Suppression Suggests Role in Retinal Electrophysiology. Sci Rep 7:10651
Carver, Kyle A; Lin, C M; Bowes Rickman, Catherine et al. (2017) Lack of the P2X7 receptor protects against AMD-like defects and microparticle accumulation in a chronic oxidative stress-induced mouse model of AMD. Biochem Biophys Res Commun 482:81-86
Walsh, Caroline E; Hitchcock, Peter F (2017) Progranulin regulates neurogenesis in the developing vertebrate retina. Dev Neurobiol 77:1114-1129
Beaudoin, Deborah L; Kupershtok, Mania; Demb, Jonathan B (2017) Selective synaptic connections in the retinal pathway for night vision. J Comp Neurol :
Seo, Seungwoon; Chen, Lisheng; Liu, Wenzhong et al. (2017) Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development. Invest Ophthalmol Vis Sci 58:1368-1377
Zhao, Xiwu; Wong, Kwoon Y; Zhang, Dao-Qi (2017) Mapping physiological inputs from multiple photoreceptor systems to dopaminergic amacrine cells in the mouse retina. Sci Rep 7:7920
Zhao, Xiwu; Reifler, Aaron N; Schroeder, Melanie M et al. (2017) Mechanisms creating transient and sustained photoresponses in mammalian retinal ganglion cells. J Gen Physiol 149:335-353

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