This NEI PSO Center Core Grant for Vision Research provides ongoing and stable funding for four high quality and productive vision research service Modules: Instrument Design, Research Computer Programming, Biostatistics and Clinical Research, and Biological Imaging. These Modules are run by an exceptionally talented staff that has long-term experience in supporting and advancing vision research at the University of Houston. The Modules provide needed research services to the present group of Core vision scientists who come from four departments at the University of Houston (Biomedical Engineering, Mechanical Engineering, Clinical Sciences and Vision Sciences in Optometry). These Core vision scientists have diverse training and research interests;they collaborate effectively with one another, as well as with more than 100 other vision researchers at this University or other institutions. Together, our Core Center investigators have 11 qualifying NEI-funded grants, as well as other NEI funding. The College of Optometry and University of Houston provide considerable additional commitments in support of vision research. During the past five years of P30 funding at this University, the Core Grant has created a favorable vision research environment that has contributed directly to 138 published papers and culminated in the recruitment of eight additional investigators to the group of Core vision scientists, four of whom brought NEI funding. The Core Grant also was crucial to the success of a clinician (OD) in obtaining new NEI funding for mentored clinician scientists. These accomplishments reflect our vision research Core's previous and current aims that focus on advancing collaborative and innovative basic, clinical and translational research to advance knowledge and prevent or cure disease. For these aims the Core grant provides stable funding, quality research services, new vision researchers, and new projects converting into NIH and NEI support. Especially emphasized in the coming five years will be innovative research basic, clinical and translational research and recruitment of vision researchers to fill our current open positions, as well as other positions in the future.

Public Health Relevance

The Center Core Grant for Vision Research at the University of Houston increases knowledge about the structure and function of the visual system, and improves visual health by supporting investigators in individual labs, and in collaborations across labs and disciplines, in doing basic, clinical and translational research on vision and vision disorders.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY007551-27
Application #
8732654
Study Section
Special Emphasis Panel (ZEY1)
Program Officer
Liberman, Ellen S
Project Start
1997-03-01
Project End
2018-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
27
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Houston
Department
Type
Schools of Optometry/Opht Tech
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77204
Saenz, Roberto; Cheng, Han; Prager, Thomas C et al. (2017) Use of A-scan Ultrasound and Optical Coherence Tomography to Differentiate Papilledema From Pseudopapilledema. Optom Vis Sci 94:1081-1089
Wang, Ye; Zhang, Bin; Tao, Xiaofeng et al. (2017) Noisy Spiking in Visual Area V2 of Amblyopic Monkeys. J Neurosci 37:922-935
Upadhyaya, Suraj; Pullela, Mythri; Ramachandran, Santoshi et al. (2017) Fixational Saccades and Their Relation to Fixation Instability in Strabismic Monkeys. Invest Ophthalmol Vis Sci 58:5743-5753
Upadhyaya, Suraj; Meng, Hui; Das, Vallabh E (2017) Electrical stimulation of superior colliculus affects strabismus angle in monkey models for strabismus. J Neurophysiol 117:1281-1292
Gesteira, Tarsis F; Sun, Mingxia; Coulson-Thomas, Yvette M et al. (2017) Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation. Invest Ophthalmol Vis Sci 58:4407-4421
Kolar, Satya Sree; Baidouri, Hasna; McDermott, Alison M (2017) Role of Pattern Recognition Receptors in the Modulation of Antimicrobial Peptide Expression in the Corneal Epithelial Innate Response to F. solani. Invest Ophthalmol Vis Sci 58:2463-2472
Liu, Chih-Hao; Schill, Alexander; Raghunathan, Raksha et al. (2017) Ultra-fast line-field low coherence holographic elastography using spatial phase shifting. Biomed Opt Express 8:993-1004
Moore, Kelly E; Benoit, Julia S; Berntsen, David A (2017) Spherical Soft Contact Lens Designs and Peripheral Defocus in Myopic Eyes. Optom Vis Sci 94:370-379
Smith 3rd, Earl L; Hung, Li-Fang; Arumugam, Baskar et al. (2017) Observations on the relationship between anisometropia, amblyopia and strabismus. Vision Res 134:26-42
Tan, Xiaochao; Banerjee, Priyam; Guo, Hou-Fu et al. (2017) Epithelial-to-mesenchymal transition drives a pro-metastatic Golgi compaction process through scaffolding protein PAQR11. J Clin Invest 127:117-131

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