The Center for Neural Science at New York University is a premier site for research on functional aspects of vision. Eighteen investigators from the Center request support for their vision research through continuation of a Core Grant. They are bound together by their research Interests In the neural and behavioral bases of vision and visually guided behavior. The proposed Core will comprise of four modules, each of which will benefit research in the research areas represented by program faculty: 1. A Visual Displays Module which will provide support for the development of state-of-the-art software for the generation of a wide variety of visual stimuli for psychophysical, neurophysiological, and brain experiments. 2. A Design and Fabrication Module which will provide expertise to design and build novel electronic and mechanical devices such as theose required for multielectrode recording in the visual cortex, noninvasive methods of eye movement recording, and Interface devices for behavioral and blloglcal experiments. 3. A Neuroanatomy and Molecular Biology Module which will provide expert support for the processing of neuroanatomlcal material at both the light and EM level, for the analysis and localization of electrophysiological recording sites In histological material, and for the creation of transgene-containing viruses to modify neuronal funtlon experimentally. 4. A Functional Imaging Module which will provide support for hardware and software services for users of the Siemens MRI scanner and associated devices In the Center for Brain Imaging, giving access for Core researchers to functional and structural Imaging capabilities for human and animal research.
NEI-funded researchers at NYU study the brain mechanisms of vision, and their work will lead to greater understanding of the basis of seeing In healthy and diseased Individuals. The Core grant will provide foundational support for their work.
|Wong, Yan T; Fabiszak, Margaret M; Novikov, Yevgeny et al. (2016) Coherent neuronal ensembles are rapidly recruited when making a look-reach decision. Nat Neurosci 19:327-34|
|Hawellek, David J; Wong, Yan T; Pesaran, Bijan (2016) Temporal coding of reward-guided choice in the posterior parietal cortex. Proc Natl Acad Sci U S A 113:13492-13497|
|Pesaran, Bijan; Freedman, David J (2016) Where Are Perceptual Decisions Made in the Brain? Trends Neurosci 39:642-644|
|Sherpa, Ang Doma; Xiao, Fanrong; Joseph, Neethu et al. (2016) Activation of Î²-adrenergic receptors in rat visual cortex expands astrocytic processes and reduces extracellular space volume. Synapse 70:307-16|
|Mitre, Mariela; Marlin, Bianca J; Schiavo, Jennifer K et al. (2016) A Distributed Network for Social Cognition Enriched for Oxytocin Receptors. J Neurosci 36:2517-35|
|Wable, Gauri S; Min, Jung-Yun; Chen, Yi-Wen et al. (2015) Anxiety is correlated with running in adolescent female mice undergoing activity-based anorexia. Behav Neurosci 129:170-82|
|Petr, Geraldine T; Sun, Yan; Frederick, Natalie M et al. (2015) Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes. J Neurosci 35:5187-201|
|Wable, G S; Chen, Y-W; Rashid, S et al. (2015) Exogenous progesterone exacerbates running response of adolescent female mice to repeated food restriction stress by changing Î±4-GABAA receptor activity of hippocampal pyramidal cells. Neuroscience 310:322-41|
|Chowdhury, Tara Gunkali; Chen, Yi-Wen; Aoki, Chiye (2015) Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa. J Vis Exp :e52927|
|Sabaliauskas, Nicole; Shen, Hui; Molla, Jonela et al. (2015) Neurosteroid effects at Î±4Î²Î´ GABAA receptors alter spatial learning and synaptic plasticity in CA1 hippocampus across the estrous cycle of the mouse. Brain Res 1621:170-86|
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