This renewal of the University of Florida's Vision Research Core grant has two overarching aims: 1. To enhance the ability of Vision Research Core investigators in various departments at the University of Florida to perform studies in vision research using state-of-the-art techniques. Vision Research Core facilities support and enhance the existing, funded research programs of its members. Moreover, it is a resource for other vision research efforts across the campus, facilitates new initiatives and ensures that the latest technology and expertise is accessible to all vision researchers. 2. To promote collaborative and multidisciplinary studies in vision research. Collaboration, communication and interchange of ideas and expertise already exist to a high degree among our investigators and departments. The shared support facilities of the Vision Research Core serve to further solidify this sense of community, bolster common goals and objectives, and increase the level of interdisciplinary research on complex problems in the visual sciences.
These aims are accomplished through Vision Research Core service modules supported by this grant, by the Department of Ophthalmology, by the College of Medicine and by the University of Florida. We propose to meet the developing needs of the University of Florida vision researchers through four modules: 1) Cell & Tissue Culture/Immunology, 2) Molecular Genetics, 3) Structural Biology/Histology and 4) In-Life Ocular Analysis. Each module offers state-of-the art instruments, services and advice, and continues to evolve to best meet the changing needs of its users in this rapidly developing era of ocular research.

Public Health Relevance

This group of NEI funded researchers with diverse expertise have, for the past 21 years, used the University of Florida's Vision Research Core services to help develop treatments for ocular maladies ranging from recessive, dominant and X-linked retinal degenerative diseases, to AMD and diabetic retinopathy to corneal scarring to Herpesviral ocular infections. This P30 support is critically important to that continued progress.

National Institute of Health (NIH)
National Eye Institute (NEI)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZEY1-VSN (05))
Program Officer
Liberman, Ellen S
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Florida
Schools of Medicine
United States
Zip Code
Prasad, Tuhina; Verma, Amrisha; Li, Qiuhong (2014) Expression and cellular localization of the Mas receptor in the adult and developing mouse retina. Mol Vis 20:1443-55
Joo, Jeong Hoon; Ryu, Danny; Peng, Qian et al. (2014) Role of Pnn in alternative splicing of a specific subset of lncRNAs of the corneal epithelium. Mol Vis 20:1629-42
Dyka, Frank M; Boye, Sanford L; Ryals, Renee C et al. (2014) Cone specific promoter for use in gene therapy of retinal degenerative diseases. Adv Exp Med Biol 801:695-701
Battelle, Barbara-Anne; Kempler, Karen E; Harrison, Alexandra et al. (2014) Opsin expression in Limulus eyes: a UV opsin is expressed in each eye type and co-expressed with a visible light-sensitive opsin in ventral larval eyes. J Exp Biol 217:3133-45
Saheb, Hady; Gedde, Steven J; Schiffman, Joyce C et al. (2014) Outcomes of Glaucoma Reoperations in the Tube Versus Trabeculectomy (TVT) Study. Am J Ophthalmol :
Jiang, Youde; Zhang, Qiuhua; Steinle, Jena J (2014) Intravitreal injection of IGFBP-3 restores normal insulin signaling in diabetic rat retina. PLoS One 9:e93788
Gibson, Daniel J; Pi, Liya; Sriram, Sriniwas et al. (2014) Conditional knockout of CTGF affects corneal wound healing. Invest Ophthalmol Vis Sci 55:2062-70
Dai, Xufeng; Han, Juanjuan; Qi, Yan et al. (2014) AAV-mediated lysophosphatidylcholine acyltransferase 1 (Lpcat1) gene replacement therapy rescues retinal degeneration in rd11 mice. Invest Ophthalmol Vis Sci 55:1724-34
Netland, Peter A; Sarkisian Jr, Steven R; Moster, Marlene R et al. (2014) Randomized, prospective, comparative trial of EX-PRESS glaucoma filtration device versus trabeculectomy (XVT study). Am J Ophthalmol 157:433-440.e3
Sriram, Sriniwas; Gibson, Daniel J; Robinson, Paulette et al. (2014) Assessment of anti-scarring therapies in ex vivo organ cultured rabbit corneas. Exp Eye Res 125:173-82

Showing the most recent 10 out of 82 publications