ADMINISTRATIVE ARRANGEMENTS Principal Investigator: Linda M. Zangwill. PhD Dr. Linda Zangwill has the necessary leadership and management skills and experience to serve as PI of the UCSD NEI Vision Research Core. As Co-Director of Clinical Research, and as Director of the Imaging Data Evaluation and Analysis (IDEA) Reading Center, she has been responsible for development and expansion of the clinical research enterprise at the Hamilton Glaucoma Center. Dr. Zangwill has had continuous ROI funding since 1995 for the Diagnostic Innovations in Glaucoma Study (DIGS): Structural Assessment, which has led to significant improvements in our ability to 1) detect glaucomatous structural damage and change, 2) understand the complex relationship between optic disc damage and visual field loss, 3) measure the rate of structural change, 4) predict who will develop progressive visual field loss. In addition, as PI for the NEI funded African Descent and Glaucoma Evaluation Study (ADAGES), OHTS and EGPS: Glaucoma detection using Confocal Scanning Laser Ophthalmoscopy and co-Investigator for the CSLO Ancillary Study to the OHTS, Dr. Zangwill has proven leadership and management skills coordinating large national and international multi-center studies, working with collaborating investigators to set priorities, and meet deadlines while maintaining an extremely productive collaborative research program. Moreover, she has been responsible for the development of an integrated data management system that provides (on a secure shared server), reading center reviewed structural, functional, clinical and demographic data acquired from the DIGS and ADAGES to collaborating researchers for analysis. This data management system required the coordination between her computer group (3 FTEs), Reading Center staff (4 FTEs) and clinical research staff (4 staff) as well as collaborating clinical researchers (at UCSD and elsewhere) and statisticians. As PI for the UCSD Vision Research Core she will bring her management expertise to work with module directors and the Advisory committee to implement a transparent decision-making process, to establish realistic expectations with clear timelines and to ensure timely response to investigator and staff concerns.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Center Core Grants (P30)
Project #
5P30EY022589-03
Application #
8689048
Study Section
Special Emphasis Panel (ZEY1-VSN)
Project Start
Project End
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
3
Fiscal Year
2014
Total Cost
$31,001
Indirect Cost
$11,000
Name
University of California San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Mundae, Rusdeep S; Zangwill, Linda M; Kabbara, Sami et al. (2017) A Longitudinal Analysis of Peripapillary Choroidal Thinning in Healthy and Glaucoma Subjects. Am J Ophthalmol :
Godisela, Kishore Kumar; Reddy, Singareddy Sreenivasa; Kumar, Chekkilla Uday et al. (2017) Impact of obesity with impaired glucose tolerance on retinal degeneration in a rat model of metabolic syndrome. Mol Vis 23:263-274
Makino, Hiroshi; Ren, Chi; Liu, Haixin et al. (2017) Transformation of Cortex-wide Emergent Properties during Motor Learning. Neuron 94:880-890.e8
Peters, Andrew J; Lee, Jun; Hedrick, Nathan G et al. (2017) Reorganization of corticospinal output during motor learning. Nat Neurosci 20:1133-1141
You, Qi Sheng; Gaber, Raouf; Meshi, Amit et al. (2017) HIGH-DOSE HIGH-FREQUENCY AFLIBERCEPT FOR RECALCITRANT NEOVASCULAR AGE-RELATED MACULAR DEGENERATION. Retina :
Yarmohammadi, Adeleh; Zangwill, Linda M; Diniz-Filho, Alberto et al. (2017) Peripapillary and Macular Vessel Density in Patients with Glaucoma and Single-Hemifield Visual Field Defect. Ophthalmology 124:709-719
Huang, Alex S; Belghith, Akram; Dastiridou, Anna et al. (2017) Automated circumferential construction of first-order aqueous humor outflow pathways using spectral-domain optical coherence tomography. J Biomed Opt 22:66010
Trakhtenberg, Ephraim F; Pita-Thomas, Wolfgang; Fernandez, Stephanie G et al. (2017) Serotonin receptor 2C regulates neurite growth and is necessary for normal retinal processing of visual information. Dev Neurobiol 77:419-437
Shoji, Takuhei; Zangwill, Linda M; Akagi, Tadamichi et al. (2017) Progressive Macula Vessel Density Loss in Primary Open-Angle Glaucoma: A Longitudinal Study. Am J Ophthalmol 182:107-117
Gaber, Raouf; You, Qi Sheng; Muftuoglu, Ilkay Kilic et al. (2017) CHARACTERISTICS OF EPIRETINAL MEMBRANE REMNANT EDGE BY OPTICAL COHERENCE TOMOGRAPHY AFTER PARS PLANA VITRECTOMY. Retina 37:2078-2083

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