The overall purpose of the Administrative Core is to help ensure the success of our COBRE grant supported investigators focused to determine mechanisms underlying neurodegenerative diseases and to identify possible treatments for these devastating illnesses. In the context of the current fight funding environment, success depends on many factors including having access to adequate space that is designed to facilitate interactions and foster excellent science, excellent mentorship, access to modern technologies, and having a nucleus of researchers with whom to collaborate. Thus, we view a concerted human effort as being essential to building further our research enterprise. Accordingly, the Administrative Core will support many essential aspects of our group's activities including (1) maintaining a centralized ordering, grant accounting and cost center system, (2) supporting our pilot research grant program, (3) supporting our mass spectrometry and imaging core facilities and their associated cost centers, (4) training investigators in how best to take advantage of the advanced technologies available to them in our Cores, (5) supporting our visiting speaker seminar series, (6) supporting specific neuroscience-related School of Medicine and Health Sciences library acquisitions, (7) organizing our annual neuroscience symposium, (8) fostering annual meetings between the three North Dakota COBRE grant supported groups and collaborations between individuals in the respective groups, and (9) supporting mentorship programs for which members of our Internal Advisory Committee and our External Advisory Board play active roles. As part of our mentorship program we will have regular meetings focusing on science, scientific collaborations, faculty-orientated survival skills, grant writing, and obtaining funding to build individual and group success. We are confident that our junior and mid-level faculty will, as a result of such committed interactions, advance their careers, increasingly publish, increasingly receive grant funding, and ultimately build this neurodegenerative disease research group to one of increased international prominence.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Center Core Grants (P30)
Project #
5P30GM103329-03
Application #
8685285
Study Section
Special Emphasis Panel (ZRR1)
Project Start
Project End
Budget Start
2014-06-01
Budget End
2015-05-31
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of North Dakota
Department
Type
DUNS #
City
Grand Forks
State
ND
Country
United States
Zip Code
58202
Golovko, Svetlana A; Golovko, Mikhail Y (2018) Plasma Unesterified Fatty-Acid Profile Is Dramatically and Acutely Changed under Ischemic Stroke in the Mouse Model. Lipids 53:641-645
Vacano, Guido N; Gibson, David S; Turjoman, Abdullah Arif et al. (2018) Proteomic analysis of six- and twelve-month hippocampus and cerebellum in a murine Down syndrome model. Neurobiol Aging 63:96-109
Quenum Zangbede, Fredice O; Chauhan, Arun; Sharma, Jyotika et al. (2018) Galectin-3 in M2 Macrophages Plays a Protective Role in Resolution of Neuropathology in Brain Parasitic Infection by Regulating Neutrophil Turnover. J Neurosci 38:6737-6750
Sukumaran, Pramod; Sun, Yuyang; Antonson, Neil et al. (2018) Dopaminergic neurotoxins induce cell death by attenuating NF-?B-mediated regulation of TRPC1 expression and autophagy. FASEB J 32:1640-1652
Sun, Yuyang; Selvaraj, Senthil; Pandey, Sumali et al. (2018) MPP+ decreases store-operated calcium entry and TRPC1 expression in Mesenchymal Stem Cell derived dopaminergic neurons. Sci Rep 8:11715
Ye, Yan; Lin, Ping; Zhang, Weidong et al. (2017) DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia. J Immunol 198:2844-2853
Colvin, Benjamin A; Rogers, Victoria A; Kulas, Joshua A et al. (2017) The conformational epitope for a new A?42 protofibril-selective antibody partially overlaps with the peptide N-terminal region. J Neurochem 143:736-749
Pu, Qinqin; Gan, Changpei; Li, Rongpeng et al. (2017) Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis in Pseudomonas Sepsis. J Immunol 198:3205-3213
Martin, Gregory G; Landrock, Danilo; Chung, Sarah et al. (2017) Fabp1 gene ablation inhibits high-fat diet-induced increase in brain endocannabinoids. J Neurochem 140:294-306
Sharma, Atul; Simonson, Tanner J; Jondle, Christopher N et al. (2017) Mincle-Mediated Neutrophil Extracellular Trap Formation by Regulation of Autophagy. J Infect Dis 215:1040-1048

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