The Core Synthesis Facility was established in 2007 to provide state-of-the-art capabilities in synthetic organic chemistry to biomedical researchers in the State of North Dakota and beyond. The core has served a wide variety of research projects in multiple disciplines on the campus and throughout the region. Its services include equipment and expertise to conduct synthetic organic chemistry and providing access to small organic compounds, potential drug molecules, and labeled molecules for biomedical studies. The core has received institutional support by way of salary and benefit contributions of 50% for the manager. Dr. Yonghua Yang, as well as the COBRE Administrative Assistant who coordinates activities between the cores. The core is expected to be an important part of the growth and development of NDSU as a recruiting tool to attract new biomedical scientists, as a cost-effective measure to stretch federal research dollars, and as a means of teaching and training investigators in chemical techniques. Outreach to educational collectives has broadened the impact of the core on science in the region.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZRR1-RI-B)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
North Dakota State University
United States
Zip Code
Singh, P; Ramamoorthy, S (2016) Lack of strong anti-viral immune gene stimulation in Torque Teno Sus Virus1 infected macrophage cells. Virology 495:63-70
Zhang, Q; Sun, M; Zhou, S et al. (2016) Class I HDAC inhibitor mocetinostat induces apoptosis by activation of miR-31 expression and suppression of E2F6. Cell Death Discov 2:16036
Singh, Pankaj; Ramamoorthy, Sheela (2016) Immune gene expression in swine macrophages expressing the Torque Teno Sus Virus1 (TTSuV1) ORF-1 and 2 proteins. Virus Res 220:33-8
Vasam, Goutham; Joshi, Shrinidh; Jarajapu, Yagna P R (2016) Impaired Mobilization of Vascular Reparative Bone Marrow Cells in Streptozotocin-Induced Diabetes but not in Leptin Receptor-Deficient db/db Mice. Sci Rep 6:26131
Buettner-Schmidt, Kelly; Miller, Donald R; Balasubramanian, Narayanaganesh (2016) Electronic Cigarette Refill Liquids: Child-Resistant Packaging, Nicotine Content, and Sales to Minors. J Pediatr Nurs 31:373-9
Joshi, Shrinidh; Balasubramanian, Narayanaganesh; Vasam, Goutham et al. (2016) Angiotensin converting enzyme versus angiotensin converting enzyme-2 selectivity of MLN-4760 and DX600 in human and murine bone marrow-derived cells. Eur J Pharmacol 774:25-33
Mei, Yang; Su, Minfei; Sanishvili, Ruslan et al. (2016) Identification of BECN1 and ATG14 Coiled-Coil Interface Residues That Are Important for Starvation-Induced Autophagy. Biochemistry 55:4239-53
Mei, Yang; Ramanathan, Arvind; Glover, Karen et al. (2016) Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated Autophagy. Biochemistry 55:1945-58
Welker, Elliott; Domfeh, Yayra; Tyagi, Deepti et al. (2015) Genetic Manipulation of Stenotrophomonas maltophilia. Curr Protoc Microbiol 37:6F.2.1-14
Qiu, Wanwei; Xu, Hui; Takalkar, Sunitha et al. (2015) Carbon nanotube-based lateral flow biosensor for sensitive and rapid detection of DNA sequence. Biosens Bioelectron 64:367-72

Showing the most recent 10 out of 75 publications