The Administrative Core of the Phase 111 COBRE application seeks to offer scientific oversight, leadership, and centralized administrative services for the University of South Carolina's biomedical research community by providing central core facilities to researchers across departments and colleges, as well as to the greater research community statewide. The Core's centralized administrative services and research core management generates significant efficiencies for both staffing and operations for all its core facilities and affiliated investigators. The Core's administrative services include: fiscal management of affiliated accounts, day-to-day operations, expert pre-award assistance (including budget development and proposal assembly and submission), and post-award grants administration to all affiliated faculty. This Core has expanded its services to include community engagement and resource development, along with being active in the recruitment of new CCCR members, facilitating intra-institutional collaborations, and organizing the CCCR's annual meeting. The Administrative Core continually evaluates its services through the ongoing consultation and evaluation by the Internal Steering Committee, the Director/PI, and the External Advisory Committee. To carry out these efforts, this Core will carry out the following aims during Phase 111: Provide central management of grant administration services, coordination of community engagement initiatives and resource development efforts. The Core provides centralized services and has developed infrastructure that fully optimizes grant administration, community engagement, and resource development services on behalf of the Center's core facilities and member investigators. Provide scientific leadership, organizational management, and ongoing evaluation of the Research Cores. It is the responsibility of the Core to provide continued research training and financial support to investigators to best facilitate their proposed research, along with implementing new research technology and overseeing the training of investigators who utilize the Center-supported cores.
Colorectal cancer is diagnosed in over 140,000 Americans each year, and takes 51,000 lives. There is need for focused research on this disease in order to identify and implement improved strategies for diagnosing, preventing, and treating it. The Administrative Core facilitates better coordination and savings within core facility use to promote the goals of the Center for Colon Cancer Research at the University of South Carolina.
|Farmaki, E; Chatzistamou, I; Kaza, V et al. (2016) A CCL8 gradient drives breast cancer cell dissemination. Oncogene 35:6309-6318|
|PeÃ±a, Edsel A; Wu, Wensong; Piegorsch, Walter et al. (2016) Model Selection and Estimation with Quantal-Response Data in Benchmark Risk Assessment. Risk Anal :|
|Kindo, Bereket P; Wang, Hao; PeÃ±a, Edsel A (2016) Multinomial probit Bayesian additive regression trees. Stat (Int Stat Inst) 5:119-131|
|Wallace, Kristin; Brandt, Heather M; Bearden, James D et al. (2016) Race and Prevalence of Large Bowel Polyps Among the Low-Income and Uninsured in South Carolina. Dig Dis Sci 61:265-72|
|Watson, Shana R; Liu, Piaomu; PeÃ±a, Edsel A et al. (2016) Comparison of Aortic Collagen Fiber Angle Distribution in Mouse Models of Atherosclerosis Using Second-Harmonic Generation (SHG) Microscopy. Microsc Microanal 22:55-62|
|Jung, Joo-Yong; Gleave Parson, Madeline; Kraft, Jennifer D et al. (2016) Elevated interleukin-27 levels in human neonatal macrophages regulate indoleamine dioxygenase in a STAT-1 and STAT-3-dependent manner. Immunology 149:35-47|
|Patel, Yogin; Shah, Nirav; Lee, Ji Shin et al. (2016) A novel double-negative feedback loop between miR-489 and the HER2-SHP2-MAPK signaling axis regulates breast cancer cell proliferation and tumor growth. Oncotarget 7:18295-308|
|Chatzistamou, Ioulia; Kiaris, Hippokratis (2016) Modeling estrogen receptor-positive breast cancers in mice: is it the best we can do? Endocr Relat Cancer 23:C9-C12|
|Broude, Eugenia V; GyÅ‘rffy, BalÃ¡zs; Chumanevich, Alexander A et al. (2015) Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer. Curr Cancer Drug Targets 15:739-49|
|Levina, Elina; Ji, Hao; Chen, Mengqiang et al. (2015) Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells. Oncotarget 6:13088-104|
Showing the most recent 10 out of 20 publications