The LSU -Tulane Center for Experimental Infectious Diseases Research (CEIDR) was established as a NIH-NCRR-supported Center of Biomedical Research Excellence (COBRE) 1P20RR020159-01 in 2004, as a strategic alliance between LSU Baton Rouge (flagship campus of the LSU System) and the Tulane National Primate Research Center (TNPRC). The overall vision of the Center has been to establish a regional center in infectious disease research led by the LSU School of Veterinary Medicine (SVM) collaborating and influenced by the substantial NIH investment in infectious disease research carried out at TNPRC. Recently, LSU-SVM and TNPRC signed a memorandum of understanding for hiring a joint faculty member and negotiations are under way to appoint a TNPRC junior faculty member in this position. After nine years of COBRE support, we are now within reach to realize our goal to develop an interdisciplinary and collaborative program in infectious diseases that addresses fundamental questions about infectious disease agents and their host interactions. CEIDR's strong mentoring has enabled 12 junior faculty during the last nine years to obtain independent NIH funding (Apetrei, Cormier, Batra, Jeyaseelan, Maclean, Kaushal, Macaluso, Liang, Mores, Pahar, Sugimoto, Embers). Additionally CEIDR has recently recruited two senior NIH-funded faculty (Martinez-LSU and Panganiban (TNPRC), while one junior faculty was recruited by NIH for a permanent staff scientist position (Peterson). Inspite of significant progress, CEIDR has not yet become a fully independent center envisioned. Our vision will be realized by completing three specific aims:1)To provide administrative and scientific infrastructure and resources to CEIDR - affiliated investigators through continued support of four essential Cores: Administrative Core (AC), GeneLab Core (GeneLab), Protein Core Laboratory(PCL), Molecular Immunopathology and Microscopy Core (MIPC);2) promote and evaluate career development and enhance research potential of CEIDR - affiliated investigators;3)transition CEIDR to a nationally recognized, interdisciplinary Infectious Disease Center of Excellence by strengthening collaborative research and academic relationships between LSU and TNPRC.

Public Health Relevance

The Center aims to attract a range of external research awards in infectious diseases and facilitate high productivity in investigator-initiated grants. CEIDR will continue to provide outstanding training environment for the next generation of infectious disease researchers with particular emphasis in training veterinarians in NlH-focused research in pursuit of the One Medicine and Comparative Medicine research.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZGM1-TWD-C (3C))
Program Officer
Zlotnik, Hinda
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Louisiana State University A&M Col Baton Rouge
Schools of Veterinary Medicine
Baton Rouge
United States
Zip Code
Verhoeve, Victoria I; Jirakanwisal, Krit; Utsuki, Tadanobu et al. (2016) Differential Rickettsial Transcription in Bloodfeeding and Non-Bloodfeeding Arthropod Hosts. PLoS One 11:e0163769
Riley, Sean P; Fish, Abigail I; Garza, Daniel A et al. (2016) Nonselective Persistence of a Rickettsia conorii Extrachromosomal Plasmid during Mammalian Infection. Infect Immun 84:790-7
Jambunathan, Nithya; Charles, Anu-Susan; Subramanian, Ramesh et al. (2016) Deletion of a Predicted β-Sheet Domain within the Amino Terminus of Herpes Simplex Virus Glycoprotein K Conserved among Alphaherpesviruses Prevents Virus Entry into Neuronal Axons. J Virol 90:2230-9
Shen, Li; Macnaughtan, Megan A; Frohlich, Kyla M et al. (2015) Multipart Chaperone-Effector Recognition in the Type III Secretion System of Chlamydia trachomatis. J Biol Chem 290:28141-55
Kaushal, Deepak; Foreman, Taylor W; Gautam, Uma S et al. (2015) Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis. Nat Commun 6:8533
Stanfield, Brent; Kousoulas, Konstantin Gus (2015) Herpes Simplex Vaccines: Prospects of Live-attenuated HSV Vaccines to Combat Genital and Ocular infections. Curr Clin Microbiol Rep 2:125-136
Baños-Lara, Ma Del Rocío; Harvey, Lindsey; Mendoza, Alexander et al. (2015) Impact and regulation of lambda interferon response in human metapneumovirus infection. J Virol 89:730-42
Charles, Anu-Susan; Chouljenko, Vladimir N; Jambunathan, Nithya et al. (2014) Phenylalanine residues at the carboxyl terminus of the herpes simplex virus 1 UL20 membrane protein regulate cytoplasmic virion envelopment and infectious virus production. J Virol 88:7618-27
McCracken, M K; Christofferson, R C; Grasperge, B J et al. (2014) Aedes aegypti salivary protein ""aegyptin"" co-inoculation modulates dengue virus infection in the vertebrate host. Virology 468-470:133-9
Gillespie, Joseph J; Driscoll, Timothy P; Verhoeve, Victoria I et al. (2014) Genomic diversification in strains of Rickettsia felis Isolated from different arthropods. Genome Biol Evol 7:35-56

Showing the most recent 10 out of 12 publications