The goal of the Nebraska Center for the Molecular Biology of Neurosensory Systems (NCNS) is to build a producfive group of researchers invesfigafing the mechanisms of neurosensory development which will provide the foundafions for new treatments. The Administrafive Core is designed to provide the infrastructure required to attain the research and infrastructure goals of the NCNS. The structures and services in the core are designed to promote the confinued growth of neurosensory and neurodeveiopmental research through 1) oversight of effective and efficient scientific cores;2) direcfion of programs to provide support;3) mentoring for pilot research;and 4) coordination with other COBRE and INBRE programs. The Administrafive Core is led by the Principal Investigator, who directs the scientific and research,mission of the NCNS, and the Program Coordinator who provides guidance and oversight for the four scientific core facilties. The PI is assisted by representafives from the two participafing insfitufions, Boys Town Nafional Research Hospital and Creighton University, forming the Execufive Committee. An internal Steering Committee is established to advise the PI in policy decisions and in the selecfion of research projects and to provide an annual evaluation. An External Advisory Committee of prominent scienfists provides further expert evaluafion for the NCNS. Our research and mentoring efforts have resulted in the development of an interactive group of productive junior and senior researchers. Our core facilities are widely used and have proven to be essential to the biomedical research enterprise at our three cooperating institutions. The continued operafion ofthe cores beyond the funding period will be assured through the application of efficient management tools in each core and the commitment of the administrative officials from all three institutions.
Research into the causes of neurodeveiopmental disorders such as hearing loss, vision loss, and aufism is necessary for the discovery of effective biomedical treatments. The Administrafive core provides the infrastructure for support and mentoring of researchers and for the building of efficient state-of-the-art core facilities. Internal and external evaluafions assure that the administrafion operates effecfively.
|Barta, Cody L; Liu, Huizhan; Chen, Lei et al. (2018) RNA-seq transcriptomic analysis of adult zebrafish inner ear hair cells. Sci Data 5:180005|
|Alsaad, Hassan A; DeKorver, Nicholas W; Mao, Zhihao et al. (2018) In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons. Neurochem Res :|
|Cruz, Eric; Kumar, Sushil; Yuan, Li et al. (2018) Intracellular amyloid beta expression leads to dysregulation of the mitogen-activated protein kinase and bone morphogenetic protein-2 signaling axis. PLoS One 13:e0191696|
|Liu, Huizhan; Chen, Lei; Giffen, Kimberlee P et al. (2018) Cell-Specific Transcriptome Analysis Shows That Adult Pillar and Deiters' Cells Express Genes Encoding Machinery for Specializations of Cochlear Hair Cells. Front Mol Neurosci 11:356|
|Wehrkamp, Cody J; Natarajan, Sathish Kumar; Mohr, Ashley M et al. (2018) miR-106b-responsive gene landscape identifies regulation of Kruppel-like factor family. RNA Biol 15:391-403|
|Lopez, Wilfredo; Page, Alexis M; Carlson, Darby J et al. (2018) Analysis of immune-related genes during Nora virus infection of Drosophila melanogaster using next generation sequencing. AIMS Microbiol 4:123-139|
|Leiferman, Amy; Shu, Jiang; Grove, Ryan et al. (2018) A diet defined by its content of bovine milk exosomes and their RNA cargos has moderate effects on gene expression, amino acid profiles and grip strength in skeletal muscle in C57BL/6 mice. J Nutr Biochem 59:123-128|
|Miura, Hiromi; Quadros, Rolen M; Gurumurthy, Channabasavaiah B et al. (2018) Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors. Nat Protoc 13:195-215|
|Won, Harim I; Schulze, Thomas T; Clement, Emalie J et al. (2018) De novo Assembly of the Burying Beetle Nicrophorus orbicollis (Coleoptera: Silphidae) Transcriptome Across Developmental Stages with Identification of Key Immune Transcripts. J Genomics 6:41-52|
|Xia, Xiaohuan; Teotia, Pooja; Ahmad, Iqbal (2018) Lin28a regulates neurogliogenesis in mammalian retina through the Igf signaling. Dev Biol 440:113-128|
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