The Histology and Imaging Core is composed of two facilities providing comprehensive imaging services to the Nebraska Center for the Molecular Biology of Neurosensory Systems (NCNS). The UNMC Tissue Sciences Facility (TSF) has been established to provide basic and specialized histology, staining, immunohistochemistry, and imaging services for studies on animal and human tissues. The TSF offers a full range of cost effective services including tissue preparation and fixing, processing, embedding, sectioning, and standard and special stains for paraffin and frozen samples. Additionally, the TSF offers both bright field and fluorescent imaging and whole slide scanning. There are many software packages available through the TSF for image analysis, reconstruction, and deconvolution as well as technical support for these programs. The resources and services at the TSF are available to all NCNS members, all University of Nebraska personnel, as well as other researchers from outside institutions and industrial users. The Integrated Biomedical Imaging Facility (IBIF) of Creighton University School of Medicine (CUSOM) provides advanced imaging capabilities to researchers of the NCNS and CUSOM and other life science researchers. Advanced imaging, which includes confocal microscopy, multi-photon confoci microsocpy, and other imaging services, is an essential componet of mdern life scicne and medical research. The IBIF has provided and continues to provide these services, plus excellent technical support, to NCNS researchers and anticipates assisting many other current and future investigators associated with the award. This facility is therefore essential to developing their future success as investigators.
Life science and medical investigations require the optimum tissue processing and imaging services to enable the discovery of the basic mechanism underiying development and disease processes. These services, ranging from basic histology to the most advanced imaging, will be provide by these two facilites to further the work of NCNS investigators.
|Barta, Cody L; Liu, Huizhan; Chen, Lei et al. (2018) RNA-seq transcriptomic analysis of adult zebrafish inner ear hair cells. Sci Data 5:180005|
|Alsaad, Hassan A; DeKorver, Nicholas W; Mao, Zhihao et al. (2018) In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons. Neurochem Res :|
|Cruz, Eric; Kumar, Sushil; Yuan, Li et al. (2018) Intracellular amyloid beta expression leads to dysregulation of the mitogen-activated protein kinase and bone morphogenetic protein-2 signaling axis. PLoS One 13:e0191696|
|Liu, Huizhan; Chen, Lei; Giffen, Kimberlee P et al. (2018) Cell-Specific Transcriptome Analysis Shows That Adult Pillar and Deiters' Cells Express Genes Encoding Machinery for Specializations of Cochlear Hair Cells. Front Mol Neurosci 11:356|
|Wehrkamp, Cody J; Natarajan, Sathish Kumar; Mohr, Ashley M et al. (2018) miR-106b-responsive gene landscape identifies regulation of Kruppel-like factor family. RNA Biol 15:391-403|
|Lopez, Wilfredo; Page, Alexis M; Carlson, Darby J et al. (2018) Analysis of immune-related genes during Nora virus infection of Drosophila melanogaster using next generation sequencing. AIMS Microbiol 4:123-139|
|Leiferman, Amy; Shu, Jiang; Grove, Ryan et al. (2018) A diet defined by its content of bovine milk exosomes and their RNA cargos has moderate effects on gene expression, amino acid profiles and grip strength in skeletal muscle in C57BL/6 mice. J Nutr Biochem 59:123-128|
|Miura, Hiromi; Quadros, Rolen M; Gurumurthy, Channabasavaiah B et al. (2018) Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors. Nat Protoc 13:195-215|
|Won, Harim I; Schulze, Thomas T; Clement, Emalie J et al. (2018) De novo Assembly of the Burying Beetle Nicrophorus orbicollis (Coleoptera: Silphidae) Transcriptome Across Developmental Stages with Identification of Key Immune Transcripts. J Genomics 6:41-52|
|Xia, Xiaohuan; Teotia, Pooja; Ahmad, Iqbal (2018) Lin28a regulates neurogliogenesis in mammalian retina through the Igf signaling. Dev Biol 440:113-128|
Showing the most recent 10 out of 72 publications