The Administrative Core will provide the administrative oversight for the Center for Molecular Medicine and the COBRE resources designed to build and strengthen the Center. The Administrative Core under the direction of Lou Hersh, the COBRE PI, and Sidney Whiteheart, Program Coordinator, will provide leadership, oversight, and coordination of the various activities associated with the Ceriter and it COBRE resources. The Administrative Core will facilitate and implement the goals and objectives of this COBRE and facilitate the transition of the Center for Molecular Medicine and its associated Cores to a sustainable independent status. The Administrative Core will provide oversight of the various activities associated with the COBRE grant including its voucher program, its pilot grant program, its mentoring activities, and its scientific cores. The Administrative Core will work with the Intemal and External Advisory Committees, and the Core directors, and to meet our goals and objectives. The Administrative Core will oversee the budgets associated with the COBRE, coordinate the various mentoring and Advisory Board meetings, track core usage, prepare reports, etc. The specific objectives of the Administrative Core include enhancing and sustaining the infrastructure of the Center for Molecular Medicine including its research core facilities, increasing the critical mass of investigators whose research focuses on the molecular basis of human disease, fostering new, collaborative and novel research in the Center providing a foundation for investigators to obtain extramural research support and to expand and develop educational activities through the scientific cores. The Administrative Core will use a number of approaches to facilitate faculty mentoring especially for junior untenured faculty, to enhance educational initiatives associated with the Center and its cores, to optimally use the pilot grant program to enhance competitive research, to facilitate programmatic grant development, and to develop collaborations with other IDeA centers and institutions in the region.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Center Core Grants (P30)
Project #
Application #
Study Section
Special Emphasis Panel (ZGM1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Kentucky
United States
Zip Code
Fontaine, Sarah N; Ingram, Alexandria; Cloyd, Ryan A et al. (2017) Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach. Neurobiol Aging 56:78-86
Shrestha, Sanjib K; Kril, Liliia M; Green, Keith D et al. (2017) Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents. Bioorg Med Chem 25:58-66
Pitsawong, Warintra; Haynes, Chad A; Koder Jr, Ronald L et al. (2017) Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase. Structure 25:978-987.e4
Wachter, Erin; Moy√°, Diego; Glazer, Edith C (2017) Combining a Ru(II) ""Building Block"" and Rapid Screening Approach to Identify DNA Structure-Selective ""Light Switch"" Compounds. ACS Comb Sci 19:85-95
Rush, Jeffrey S; Edgar, Rebecca J; Deng, Pan et al. (2017) The molecular mechanism of N-acetylglucosamine side-chain attachment to the Lancefield group A carbohydrate in Streptococcus pyogenes. J Biol Chem 292:19441-19457
Sikora, Aleksandra E; Mills, Robert H; Weber, Jacob V et al. (2017) Peptide Inhibitors Targeting the Neisseria gonorrhoeae Pivotal Anaerobic Respiration Factor AniA. Antimicrob Agents Chemother 61:
Webb, Stacy; Nagy, Tamas; Moseley, Hunter et al. (2017) Hendra virus fusion protein transmembrane domain contributes to pre-fusion protein stability. J Biol Chem 292:5685-5694
Wagner, Jonathan M; Chan, Sum; Evans, Timothy J et al. (2016) Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. BMC Struct Biol 16:5
Frasinyuk, Mykhaylo S; Mrug, Galyna P; Bondarenko, Svitlana P et al. (2016) Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases. ChemMedChem 11:600-11
Sviripa, Vitaliy M; Burikhanov, Ravshan; Obiero, Josiah M et al. (2016) Par-4 secretion: stoichiometry of 3-arylquinoline binding to vimentin. Org Biomol Chem 14:74-84

Showing the most recent 10 out of 33 publications